Synthesis of Isoxazolopyridines and Spirooxindoles under Ultrasonic Irradiation and Evaluation of Their Antioxidant Activity

被引：9
|
作者：
Pelit, Emel [1 ]
机构：
[1] Kirklareli Univ, Dept Chem, Fac Art & Sci, Kayali Campus, TR-39100 Kirklareli, Turkey
来源：
JOURNAL OF CHEMISTRY | 2017年 / 2017卷
关键词：
MULTICOMPONENT REACTIONS; EFFICIENT SYNTHESIS; EASY ACCESS; CATALYST; DERIVATIVES; DIVERSITY; CHEMISTRY;
D O I：
10.1155/2017/9161505
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
New polycyclic-fused isoxazolo[4,5-e] pyridines and spirooxindoles were obtained via multicomponent reaction of 5-amino-3-methylisoxazole, indan-1,3-dione, and aromatic aldehydes and reaction of 5-amino-3-methylisoxazole, isatin, and beta-diketones in the presence of (+/-)-camphor-10-sulfonic acid as an effective and nontoxic organocatalyst under ultrasound-promoted conditions. The antioxidant activity of the novel synthesized compounds was studied.
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页数：9
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