Tripterygium wilfordii Hook F. versus Sulfasalazine in the treatment of rheumatoid arthritis: A well-designed clinical trial of a botanical demonstrating effectiveness

被引:33
|
作者
Marks, William H. [1 ]
机构
[1] Alexion Pharmaceut, Cheshire, CT 06410 USA
关键词
Tripterygium; Thundergod vine; Rheumatoid arthritis; Traditional Chinese medicine; Disease Modifying Anti-Rheumatic drugs (DMARD); MEDICINE; DECLINE;
D O I
10.1016/j.fitote.2010.11.024
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Claims that Traditional/Alternative medicine (TM/AM) remedies are effective are routinely ignored by Western Medicine. However, the results of a clinical trial that demonstrated the clinical efficacy of Tripterygium wilfordii Hook F. (TW), a TM used as an anti-inflammatory, were recently published in the Annals of Internal Medicine. Why this article was published in a peer reviewed Allopathic medical journal is an important question that begs examination and may lay the future promise of TM/AM therapeutic interventions. (C) 2010 Published by Elsevier B.V.
引用
收藏
页码:85 / 87
页数:3
相关论文
共 39 条
  • [21] Comment on: 'Comparison of Tripterygium wilfordii Hook F with methotrexate in the treatment of active rheumatoid arthritis (TRIFRA): a randomised, controlled clinical trial' by Qian-wen et al
    Landewe, Robert B. M.
    van der Heijde, Desiree
    ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 (10) : E62 - E62
  • [22] Extracts of Tripterygium wilfordii Hook F in the Treatment of Rheumatoid Arthritis: A Systemic Review and Meta-Analysis of Randomised Controlled Trials
    Liu, Yafei
    Tu, Shenghao
    Gao, Weina
    Wang, Yu
    Liu, Peilin
    Hu, Yonghong
    Dong, Hui
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2013, 2013
  • [23] Efficacy and Safety of Tripterygium wilfordii Hook F Versus Acitretin in Moderate to Severe Psoriasis Vulgaris: A Randomized Clinical Trial
    Wu Chao
    Jin Hong-Zhong
    Shu Dan
    Li Feng
    He Chun-Xia
    Qiao Ju
    Yu Xiao-Ling
    Zhang Ying
    He Yi-Bo
    Liu Tie-Jun
    中华医学杂志英文版, 2015, 128 (04) : 443 - 449
  • [24] Efficacy of adalimumab combined with Tripterygium wilfordii Hook F in the treatment of patient with rheumatoid arthritis: A multicenter, open-label, randomized-controlled trial
    Luo, Feng
    Gau, Shuo-Yan
    Wu, Yu-xia
    Liao, Hou-li
    Tang, Fang
    Zhong, Qin
    Huang, Ying
    Hou, Lei
    Liu, Zheng-qi
    Cai, Jin-long
    Cao, Yue-peng
    Lu, Dao-min
    An, Yang
    Lan, Wei-ya
    Liu, Can
    Chen, Chang-ming
    Jia, Er-tao
    Yao, Xue-ming
    Wei, James Cheng-Chung
    Ma, Wu-kai
    INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 2024, 27 (01)
  • [25] The Safety and Effectiveness of a Chloroform/Methanol Extract of Tripterygium wilfordii Hook F (T2) Plus Methotrexate in Treating Rheumatoid Arthritis
    Zhang, Wen
    Shi, Qun
    Zhao, Li-dan
    Li, Yang
    Tang, Fu-lin
    Zhang, Feng-chun
    Zhang, Xuan
    JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 2010, 16 (08) : 375 - 378
  • [26] Efficacy and Safety of Tripterygium wilfordii Hook F Versus Acitretin in Moderate to Severe Psoriasis Vulgaris: A Randomized Clinical Trial
    Wu, Chao
    Jin, Hong-Zhong
    Shu, Dan
    Li, Feng
    He, Chun-Xia
    Qiao, Ju
    Yu, Xiao-Ling
    Zhang, Ying
    He, Yi-Bo
    Liu, Tie-Jun
    CHINESE MEDICAL JOURNAL, 2015, 128 (04) : 443 - 449
  • [27] Response to DM Marcus's comment on the TRIFRA study (comparison of Tripterygium wilfordii Hook F vs methotrexate in the treatment of active rheumatoid arthritis)
    Lv, Qian-wen
    Zhang, Wen
    Shi, Qun
    Zheng, Wen-jie
    Lipsky, Peter E.
    Zhang, Xuan
    ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 (09) : E57 - E57
  • [28] A multi-center, double blind, randomized study in patients with active rheumatoid arthritis (RA) comparing an extract from a Chinese vine, tripterygium wilfordii hook F (TWHF), to sulfasalazine.
    Goldbach-Mansky, Raphaela T.
    Wilson, Mildred
    Alli, Shaan
    Pham, Tuyet H.
    Kivitz, Alan
    Silverfield, Joel
    Kempf, Philip
    Olsen, Nancy
    Fleischmann, Roy
    Tao, Xuelian
    Lipsky, Peter E.
    ARTHRITIS AND RHEUMATISM, 2006, 54 (09): : S238 - S238
  • [29] Effect of cream, prepared with Tripterygium wilfordii Hook F and other four medicinals, on joint pain and swelling in patients with rheumatoid arthritis: a double-blinded, randomized, placebo controlled clinical trial
    Jiao Juan
    Wei Chengchung
    Tang Xiaopo
    Gong Xun
    Yin Haibo
    Jiang Quan
    JournalofTraditionalChineseMedicine, 2019, 39 (01) : 89 - 96
  • [30] A phase I/II double-blind, placebo-controlled trial of an extract of Tripterygium wilfordii Hook F shows benefit in patients with rheumatoid arthritis.
    Tao, XLC
    Pinyopompanit, V
    Younger, J
    Cai, JJ
    Mao, YP
    Ma, L
    Chang, S
    Lipsky, PE
    ARTHRITIS AND RHEUMATISM, 2001, 44 (09): : S370 - +