Tramadol Treatment for Chemotherapy-induced Mucositis Pain in Children

被引：4

作者：

Yaffe Ornstein, Michal ^{[1
]}

Stocki, Daniel ^{[2
]}

Levin, Dror ^{[1
]}

Dvir, Rina ^{[1
]}

Manisterski, Michal ^{[1
]}

Berger-Achituv, Sivan ^{[1
]}

Rosenfeld Keidar, Hila ^{[1
]}

Peled, Yair ^{[1
]}

Hazan, Shoshana ^{[2
]}

Rosenberg, Tom ^{[1
]}

Oppenheimer, Noga ^{[1
]}

Elhasid, Ronit ^{[1
]}

机构：

[1] Tel Aviv Univ, Tel Aviv Med Ctr, Sackler Fac Med, Dept Pediat Hematooncol, Tel Aviv, Israel

[2] Tel Aviv Univ, Tel Aviv Med Ctr, Sackler Fac Med, Dept Anesthesia Intens Care & Pain Div, Tel Aviv, Israel

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2022年 / 44卷 / 02期

关键词：

mucositis; tramadol; children; chemotherapy; pain; ORAL MUCOSITIS; MANAGEMENT;

D O I：

10.1097/MPH.0000000000002003

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mucositis, a painful and debilitating condition, is a common side effect of chemotherapy. The role of tramadol in the treatment of mucositis in pediatric patients has not yet been determined. In this retrospective study, we evaluate whether tramadol as single agent achieved a reduction of pain intensity among oncologic children admitted for mucositis. In total, 34 of 54 (63%) episodes were treated with tramadol alone and achieved adequate pain relief. Tramadol's side effects were mild and manageable.

引用

页码：E487 / E492

页数：6

共 50 条

[21] Palifermin and chemotherapy-induced oral mucositis - Reply
Spielberger, R
Stiff, P
Bensinger, W
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (12): : 1265 - 1265
[22] RELATIONSHIP OF CHEMOTHERAPY-INDUCED MUCOSITIS AND MYELOSUPPRESSION IN HAMSTERS
SONIS, S
KOPLOWSKY, A
MITUS, J
ROSENTHAL, D
BRAND, M
ORAL ONCOLOGY-EUROPEAN JOURNAL OF CANCER PART B, 1992, 28B (01): : 43 - 43
[23] Chemotherapy-induced and/or radiation therapy-induced oral mucositis - Complicating the treatment of cancer
Naidu, MUR
Ramana, GV
Rani, PU
Mohan, IK
Suman, A
Roy, P
NEOPLASIA, 2004, 6 (05): : 423 - 431
[24] Patients with moderate chemotherapy-induced mucositis: pain therapy using low intensity lasers
Nes, A. G.
INTERNATIONAL NURSING REVIEW, 2005, 52 (01) : 68 - 72
[25] Use of the Rat Grimace Scale to Evaluate Visceral Pain in a Model of Chemotherapy-Induced Mucositis
George, Rebecca P.
Howarth, Gordon S.
Whittaker, Alexandra L.
ANIMALS, 2019, 9 (09):
[26] Treatment of chemotherapy-induced emesis in children.
Guitteny, MA
Pajot, C
Chalumeau, M
Pein, F
Grill, J
Hartmann, O
ARCHIVES DE PEDIATRIE, 1998, 5 (06): : 661 - 668
[27] Glucagon-like peptide-1 as a treatment for chemotherapy-induced mucositis
Kissow, Hannelouise
Hartmann, Bolette
Holst, Jens Juul
Poulsen, Steen Seier
GUT, 2013, 62 (12) : 1724 - 1733
[28] Chemotherapy-Induced Oral Mucositis: Effect of LED and Laser Phototherapy Treatment Protocols
Carneiro Freitas, Ana Carolina
Campos, Luana
Brandao, Thais Bianca
Cristofaro, Marcio
Eduardo, Fernanda de Paula
Luiz, Ana Claudia
Marques, Marcia Martins
Eduardo, Carlos de Paula
Simoes, Alyne
PHOTOMEDICINE AND LASER SURGERY, 2014, 32 (02) : 81 - 87
[29] Evidence Supporting the use of Probiotics for the Prevention and Treatment of Chemotherapy-Induced Intestinal Mucositis
Prisciandaro, Luca D.
Geier, Mark S.
Butler, Ross N.
Cummins, Adrian G.
Howarth, Gordon S.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2011, 51 (03) : 239 - 247
[30] SPAK Deficiency Attenuates Chemotherapy-Induced Intestinal Mucositis
Huang, Tien-Yu
Yang, Sung-Sen
Liao, Ching-Len
Lin, Ming-Hong
Lin, Hsuan-Hwai
Lin, Jung-Chun
Chen, Peng-Jen
Shih, Yu-Lueng
Chang, Wei-Kuo
Hsieh, Tsai-Yuan
FRONTIERS IN ONCOLOGY, 2021, 11

← 1 2 3 4 5 →