Elucidation of triacylglycerols in cod liver oil by liquid chromatography electrospray tandem ion-trap mass spectrometry

被引：27
|
作者：
Zeng, Ying-Xu [1 ,2 ,3 ]
Araujo, Pedro [1 ]
Du, Zhen-Yu [1 ]
Nguyen, Thu-Thao [1 ]
Froyland, Livar [1 ]
Grung, Bjorn [2 ]
机构：
[1] Natl Inst Nutr & Seafood Res NIFES, N-5817 Bergen, Norway
[2] Univ Bergen, Dept Chem, N-5009 Bergen, Norway
[3] Univ Algarve, Fac Sci & Technol, P-8005139 Faro, Portugal
来源：
TALANTA | 2010年 / 82卷 / 04期
关键词：
Cod liver oil; Triacylglycerols; Fatty acids; Liquid chromatography electrospray tandem mass spectrometry; Algorithm; NUCLEAR-MAGNETIC-RESONANCE; TRIACYL-SN-GLYCEROLS; FATTY-ACIDS; POSITIONAL DISTRIBUTION; STEREOSPECIFIC ANALYSIS; DOCOSAHEXAENOIC ACID; C-13-NMR SPECTROSCOPY; RHEUMATOID-ARTHRITIS; MARINE OILS; FISH OILS;
D O I：
10.1016/j.talanta.2010.06.055
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Though liquid chromatography electrospray tandem mass spectrometry (LC-ESI-MS2) has been widely used in the structural elucidation of triacylglycerols (TAG) in vegetable oils, its potentiality for the identification of TAG molecules in omega-3 rich oils remains unexplored till date. Hence, this article investigates the applicability of LC-ESI-MS2 for the structural characterization of naturally occurring TAG in cod liver oil without the TAG fractionation during the sample preparation. A computational algorithm was developed to automatically interpret the mass spectra and elucidate the TAG structures respectively. The results were compared against the lipase benchmark method. A principal component analysis study revealed that it is possible to discriminate genuine from adulterated cod liver oil. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码：1261 / 1270
页数：10
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