Pd/C-Mediated Dual C-C Bond Forming Reaction in Water: Synthesis of 2,4-Dialkynylquinoline

被引：3

作者：

Reddy, Ellanki A. ^{[2
,3
]}

Islam, Aminul ^{[3
]}

Mukkanti, K. ^{[2
]}

Venu, Bolla K. ^{[3
]}

Pal, Manojit ^{[1
]}

机构：

[1] Matrix Labs Ltd, R&D Ctr, New Drug Discovery, Jinnaram Mandal 502325, Andra Pradesh, India

[2] JNT Univ, Inst Sci & Technol, Div Chem, Hyderabad 500072, Andhra Pradesh, India

[3] Dr Reddys Labs Ltd, Hyderabad 500049, Andhra Pradesh, India

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2010年 / 21卷 / 09期

关键词：

quinoline; palladium; charcoal; copper; C-C bond; alkyne; COUPLING REACTIONS;

D O I：

10.1590/S0103-50532010000900012

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pd/C facilitated dual C-C bond forming reaction between 2,4-diiodoquinoline and terminal alkynes in water providing a practical and one-step synthesis of 2,4-dialkynylquinolines. A number of related quinoline derivatives were prepared in good to excellent yields using this water-based methodology. The use of other palladium catalysts and solvents was examined and the mechanism of the reaction has been discussed.

引用

页码：1681 / 1687

页数：7

共 50 条

[21] Bronsted acid-catalyzed C-C bond forming reaction for one step synthesis of oxazinanones
Uddin, Nazim
Ulicki, Joseph S.
Foersterling, F. Holger
Hossain, M. Mahmun
TETRAHEDRON LETTERS, 2011, 52 (33) : 4353 - 4356
[22] Csp2-O and C-C Bond Formation via Pd-Catalyzed Coupling Reaction of 2,4-Dichloroquinazoline
Sharma, Alka
Luxami, Vijay
Paul, Kamaldeep
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2016, 53 (01) : 241 - 248
[23] Synthesis of carbon nanotube supported Pd catalysts and evaluation of their catalytic properties for C-C bond forming reactions
Kim, Ja Young
Jo, Youngshin
Kook, Seong-Keun
Lee, Sunwoo
Choi, Hyun Chul
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2010, 323 (1-2) : 28 - 32
[24] A New and Direct Synthesis of Chalcones Via TFAA-H3PO4 Mediated C-C Bond Forming Reaction
Kankanala, Kavitha
Reddy, Lingam Venkata
Reddy, Vangala Ranga
Mukkanti, Khagga
Pal, Sarbani
LETTERS IN ORGANIC CHEMISTRY, 2011, 8 (01) : 53 - 59
[25] Synthesis and stereoselective C-C bond-forming reactions of peptide aldehydes
Reetz, MT
Griebenow, N
LIEBIGS ANNALEN, 1996, (03): : 335 - 348
[26] ASYMMETRIC C-C BOND-FORMING REACTIONS
MEYERS, AI
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 208 : 161 - ORGN
[27] C-C bond-forming desulfurizations of sulfoximines
Reggelin, M.
Slavik, S.
Buehle, P.
ORGANIC LETTERS, 2008, 10 (18) : 4081 - 4084
[28] Enzyme mediated C-C bond formation
Fessner, WD
CURRENT OPINION IN CHEMICAL BIOLOGY, 1998, 2 (01) : 85 - 97
[29] Enantioselective C-C bond forming reactions.
Evans, DA
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 213 : 466 - ORGN
[30] Asymmetric C-C bond forming method for the synthesis of smoking cessation agents
Koduri, Naga Durgarao
Hussaini, Syed R.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243

← 1 2 3 4 5 →