Expression of c-fos in the rat brainstem after chronic intermittent hypoxia

被引：86

作者：

Greenberg, HE ^{[1
]}

Sica, AL

Scharf, SM

Ruggiero, DA

机构：

[1] Long Isl Jewish Med Ctr, Div Pulm & Crit Care Med, New Hyde Park, NY 11040 USA

[2] Columbia Univ Coll Phys & Surg, Dept Psychiat, New York, NY 10032 USA

[3] Columbia Univ Coll Phys & Surg, Dept Anat & Cell Biol, New York, NY 10032 USA

[4] Neurol Res Inst Lubec, Lubec, ME 04652 USA

来源：

BRAIN RESEARCH | 1999年 / 816卷 / 02期

基金：

美国国家卫生研究院;

关键词：

intermittent hypoxia c-fos; sympathetic nervous system; obstructive sleep apnea;

D O I：

10.1016/S0006-8993(98)01222-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Chronic intermittent hypoxia(CIH) may cause sustained systemic hypertension by increasing sympathetic neural discharge (SND). We hypothesized that CM alters brainstem circuits modulating SND. After 30 days of CIH exposure in rats, increased c-fas labeling was seen in the nucleus of the solitary tract and ventrolateral medulla as well as other brainstem regions involved in regulation of SND. Increased expression of c-fas after CIH may indicate changes in neuronal genetic transcription which ultimately modulate SND. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：638 / 645

页数：8

共 50 条

[41] Immunohistochemical estimation of c-fos expression in rat lumbar spinal cord after inflammation
Orendacova, J
CHEMICKE LISTY, 1996, 90 (09): : 767 - 768
[42] Accelerated breakdown and enhanced expression of c-Fos in the rat brain after noxious stimulation
Redburn, JL
Leah, JD
NEUROSCIENCE LETTERS, 1997, 237 (2-3) : 97 - 100
[43] Effect of subdiaphragmatic vagotomy on jejunal motility and c-Fos expression in brainstem nuclei after intestinal anaphylaxis.
Scott, RB
Tan, DTM
Sharkey, KA
GASTROENTEROLOGY, 1997, 112 (04) : A822 - A822
[44] Behavioural, autonomic and endocrine responses associated with c-fos expression in the forebrain and brainstem after intracerebroventricular infusions of endothelins
Zhu, B
Herbert, J
NEUROSCIENCE, 1996, 71 (04) : 1049 - 1062
[45] Isoflurane induces c-Fos expression in the area postrema of the rat
Hase, Tetsutaro
Hashimoto, Toshikazu
Saito, Hitoshi
Uchida, Yosuke
Kato, Rui
Tsuruga, Kenkichi
Takita, Koichi
Morimoto, Yuji
JOURNAL OF ANESTHESIA, 2019, 33 (04) : 562 - 566
[46] C-fos expression in rat brain during heat stress
Lin, MT
Yang, YL
Tsay, HJ
JOURNAL OF THERMAL BIOLOGY, 1999, 24 (5-6) : 423 - 427
[47] Effects of olanzapine on regional c-Fos expression in rat forebrain
Robertson, GS
Fibiger, HC
NEUROPSYCHOPHARMACOLOGY, 1996, 14 (02) : 105 - 110
[48] The impact of hearing experience on signal integration in the auditory brainstem: A c-Fos study of the rat
Rosskothen-Kuhl, Nicole
Illing, Robert-Benjamin
BRAIN RESEARCH, 2012, 1435 : 40 - 55
[49] c-Fos, Arc, and Stargazin Expression in Rat Eyeblink Conditioning
Kim, Soyun
Thompson, Richard F.
BEHAVIORAL NEUROSCIENCE, 2011, 125 (01) : 117 - 123
[50] MORPHINE ACTIVATION OF C-FOS EXPRESSION IN RAT-BRAIN
CHANG, SL
SQUINTO, SP
HARLAN, RE
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 157 (02) : 698 - 704

← 1 2 3 4 5 →