Disseminated blastomycosis in a patient with polycythemia vera on ruxolitinib

被引：1
|
作者：
Zeitler, Kristen [1 ]
Jariwala, Ripal [2 ]
Alrabaa, Sally [3 ]
Sriaroon, Chakrapol [4 ]
机构：
[1] Tampa Gen Hosp, Dept Pharm, Tampa, FL 33606 USA
[2] Univ Calif San Francisco, Dept Pharm, San Francisco, CA USA
[3] Univ S Florida, Div Infect Dis & Int Med, Dept Internal Med, Tampa, FL 33620 USA
[4] Univ S Florida, Pulm Crit Care, Tampa, FL 33620 USA
来源：
BMJ CASE REPORTS | 2021年 / 14卷 / 11期
关键词：
infections; malignant disease and immunosuppression; INFECTIONS;
D O I：
10.1136/bcr-2021-243694
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Ruxolitinib (RUX) is a kinase inhibitor used in the treatment of various medical conditions and its mechanism of action involves suppression of the immune system. While beneficial in treatment of polycythemia vera, myelofibrosis and other indications, it can also increase a patient's susceptibility to various infections, including bacterial, viral and fungal. We present a case of a patient being treated with RUX who presented with a disseminated fungal infection. This case emphasises the need for vigilance of endemic fungal infections in individuals who are on RUX therapy.
引用
收藏
页数：4
相关论文
共 50 条
  • [41] Combination Therapy with Ruxolitinib and Interferon in Newly Diagnosed Patients with Polycythemia Vera
    Sorensen, Anders Lindholm Lindholm
    Skov, Vibe
    Kjaer, Lasse
    Eickhardt-Dalboge, Christina Schjellerup Schjellerup
    Larsen, Morten Kranker
    Nielsen, Claus
    Thomsen, Carsten
    Gjerdrum, Lise Mette Rahbek
    Knudsen, Trine Alma
    Ellervik, Christina
    Overgaard, Ulrik Malthe
    Andersen, Christen Lykkegaard
    Bjorn, Mads Emil
    Hasselbalch, Hans Carl
    BLOOD, 2022, 140 : 6806 - 6807
  • [42] Ruxolitinib for polycythemia vera and essential thrombocytosis: a single-center experience
    Ekinci, O.
    Merter, M.
    LEUKEMIA RESEARCH, 2019, 85 : S55 - S55
  • [43] Interferon for any patient with polycythemia vera?
    Cailly, Laura
    Cayssials, Emilie
    Torregrosa-Diaz, Jose-Miguel
    HEMATOLOGIE, 2021, 27 (02): : 48 - 50
  • [44] Splenocolic fistula in a patient with polycythemia vera
    Means, JR
    Villella, DR
    Stahlfeld, KR
    AMERICAN JOURNAL OF SURGERY, 2003, 185 (02): : 173 - 174
  • [45] ESOPHAGEAL VARICES IN A POLYCYTHEMIA VERA PATIENT
    Abdalla, Tarek
    Thummathati, Soujanya
    Smalligan, Roger D.
    JOURNAL OF GENERAL INTERNAL MEDICINE, 2018, 33 : S514 - S515
  • [46] Diagnosis of polycythemia vera in an anemic patient
    Hassoun, H
    Pavlovsky, M
    Mansoor, S
    Stopka, T
    SOUTHERN MEDICAL JOURNAL, 2000, 93 (07) : 710 - 712
  • [47] ANHIDROSIS IN PATIENT WITH POLYCYTHEMIA-VERA
    VALENTIN.WN
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1974, 228 (05): : 626 - 626
  • [48] IgA nephropathy in a patient with polycythemia vera
    Chung, J
    Park, PG
    Song, KI
    AMERICAN JOURNAL OF NEPHROLOGY, 2002, 22 (04) : 397 - 401
  • [49] ULCERATIVE LYMPHANGIOMA IN A PATIENT WITH POLYCYTHEMIA VERA
    DOUGHERTY, JW
    WORTHINGTON
    AMA ARCHIVES OF DERMATOLOGY AND SYPHILOLOGY, 1954, 69 (04): : 514 - 515
  • [50] Ruxolitinib In The Treatment Of Polycythemia Vera: An Update On Health-Related Quality Of Life And Patient-Reported Outcomes
    Cingam, Shashank
    Flatow-Trujillo, Lainey
    Andritsos, Leslie A.
    Yi, Cecilia Arana
    JOURNAL OF BLOOD MEDICINE, 2019, 10 : 381 - 390
12345