Design, synthesis and SAR of novel inhibitors for glutamate racemase (RacE2) from Bacillus anthracis

被引:0
|
作者
Gao, Kuanqiang [1 ]
Wang, Zhiqiang [2 ]
Mulhearn, Debbie C. [1 ]
Yu, Huidong [1 ]
Thatcher, Gregory R. J. [2 ]
Johnson, Michael E. [1 ]
机构
[1] Univ Illinois, Ctr Pharmaceut Biotechnol, Chicago, IL 60607 USA
[2] Univ Illinois, Dept Med Chem & Pharmacognosy, Chicago, IL 60612 USA
来源
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 233卷
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
453-MEDI
引用
收藏
页码:780 / 780
页数:1
相关论文
共 50 条
  • [21] Design, synthesis and SAR studies of novel survivin inhibitors with potent antiproliferative properties
    Xiao, Min
    Wang, Jin
    Lu, Yan
    Miller, Duane D.
    Li, Wei
    CANCER RESEARCH, 2015, 75
  • [22] Design, Synthesis and SAR Studies of Novel and Potent Dipeptidyl Peptidase 4 Inhibitors
    Luo, Na
    Fang, Xiaoyu
    Su, Mingbo
    Zhang, Xinwen
    Li, Dan
    Li, Honglin
    Li, Shiliang
    Zhao, Zhenjiang
    CHINESE JOURNAL OF CHEMISTRY, 2021, 39 (01): : 115 - 120
  • [23] Design of Helicobacter pylori glutamate racemase inhibitors as selective antibacterial agents:: A novel pro-drug approach to increase exposure
    Basarab, Gregory S.
    Hill, Pamela J.
    Rastagar, Abdullah
    Webborn, Peter J. H.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (16) : 4716 - 4722
  • [24] MEDI 575-Design, synthesis, and SAR of novel benzimidazole based HDAC inhibitors
    Wang, Haishan
    Yu, Niefang
    Song, Hongyan
    Chen, Dizhong
    Deng, Weiping
    Lye, Pek Ling
    Zou, Yong
    Ng, Melvin
    Chang, Joyce
    Sun, Eric T.
    Sangthongpitag, Kanda
    Wang, Xukun
    Wu, Xiaofeng
    Khng, Hwee Hoon
    Goh, Siok Kun
    Yeo, Pauline
    Liu, Xin
    Goh, Evelyn
    New, Lee Sun
    Ethirajulu, Kantharaj
    Entzeroth, Michael
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232
  • [25] Design, synthesis, and SAR of a novel series of p38α MAP kinase inhibitors
    Martin, Barrie P.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 241
  • [26] The design and synthesis of novel cyclooxygenase-2 inhibitors
    Woods, KW
    McCroskey, RW
    Michaelides, MR
    Wada, CK
    Hulkower, KI
    Bell, RL
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 214 : 92 - MEDI
  • [27] Crystal structure of 7,8-dihydropteroate synthase from Bacillus anthracis:: Mechanism and novel inhibitor design
    Babaoglu, K
    Qi, JJ
    Lee, RE
    White, SW
    STRUCTURE, 2004, 12 (09) : 1705 - 1717
  • [28] Crystal structure of dihydropteroate synthase from Bacillus anthracis:: Studies into mechanism and starting point for novel inhibitor design
    Babaoglu, K
    Qi, J
    Lee, RE
    White, SW
    PROTEIN SCIENCE, 2004, 13 : 85 - 85
  • [29] Design, synthesis and SAR study of novel C2-pyrazolopyrimidine amides and amide isosteres as allosteric integrase inhibitors
    Patel, Manoj
    Cianci, Christopher
    Allard, Christopher W.
    Parker, Dawn D.
    Simmermacher, Jean
    Jenkins, Susan
    Mcauliffe, Brian
    Minassian, Beatrice
    Discotto, Linda
    Krystal, Mark
    Meanwell, Nicholas A.
    Naidu, B. Narasimhulu
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 30 (21)
  • [30] Design, synthesis and SAR evaluation of novel inhibitors of poly(ADP-ribose)polymerase (PARP).
    Musick, KY
    Weintraub, PM
    Eastwood, P
    Mehdi, S
    Koehl, J
    Kominos, D
    Schreuder, H
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 226 : U22 - U22