In vivo comparison of three novel radiotracers for the NMDA receptor GluN2B subunit in non-human primates

被引:0
|
作者
Smart, Kelly [1 ]
Zheng, MingQiang [1 ]
Ahmed, Hazem [2 ]
Fang, Hanyi [1 ,3 ]
Xu, Yuping [1 ,4 ]
Cai, Lisheng [5 ]
Holden, Daniel [1 ]
Kapinos, Michael [1 ]
Felchner, Zachary [1 ]
Ropchan, Jim [1 ]
Tamagnan, Gilles [1 ]
Innis, Robert [5 ]
Pike, Victor [5 ]
Ametamey, Simon [2 ]
Huang, Henry [1 ]
Carson, Richard [1 ]
机构
[1] Yale Univ, PET Ctr, New Haven, CT USA
[2] Swiss Fed Inst Technol, Inst Pharmaceut Sci, Zurich, Switzerland
[3] Huazhong U, Dept Nucl Med, Union Hosp, Tongji Med Coll, Wuhan, Peoples R China
[4] Jiangsu Inst Nucl Med, Wuxi, Jiangsu, Peoples R China
[5] NIMH, Mol Imaging Branch, Bethesda, MD 20892 USA
关键词
D O I
暂无
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
46
引用
收藏
页数:3
相关论文
共 50 条
  • [41] GluN2B subunit-containing NMDA receptor antagonists prevent Aβ-mediated synaptic plasticity disruption in vivo (vol 106, pg 20504, 2009)
    Hu, Neng-Wei
    Klyubin, Igor
    Anwyl, Roger
    Rowan, Michael J.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (28) : 12734 - 12734
  • [42] Ghrelin upregulates the phosphorylation of the GluN2B subunit of the NMDA receptor by activating GHSR1a and Fyn in the rat hippocampus
    Berrout, Liza
    Isokawa, Masako
    BRAIN RESEARCH, 2018, 1678 : 20 - 26
  • [43] Dynamic regulation of phosphorylation of NMDA receptor GluN2B subunit tyrosine residues mediates ketamine rapid antidepressant effects
    Wang, Ke
    Tan, Xuan
    Ding, Kai-Mo
    Feng, Xue-Zhu
    Zhao, Yu-Yu
    Zhu, Wei-Li
    Li, Guo-Hai
    Li, Su-Xia
    PHARMACOLOGICAL RESEARCH, 2024, 205
  • [44] Specificity protein 4 functionally regulates the transcription of NMDA receptor subunits GluN1, GluN2A, and GluN2B
    Priya, Anusha
    Johar, Kaid
    Wong-Riley, Margaret T. T.
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2013, 1833 (12): : 2745 - 2756
  • [45] Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains
    Swanger, Sharon A.
    Chen, Wenjuan
    Wells, Gordon
    Burger, Pieter B.
    Tankovic, Anel
    Bhattacharya, Subhrajit
    Strong, Katie L.
    Hu, Chun
    Kusumoto, Hirofumi
    Zhang, Jing
    Adams, David R.
    Millichap, John J.
    Petrovski, Slave
    Traynelis, Stephen F.
    Yuan, Hongjie
    AMERICAN JOURNAL OF HUMAN GENETICS, 2016, 99 (06) : 1261 - 1280
  • [46] The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B
    Ka Hing Tsang
    Suk King Lai
    Qi Li
    Wing Ho Yung
    Hang Liu
    Priscilla Hoi Shan Mak
    Cypress Chun Pong Ng
    Grainne McAlonan
    Ying Shing Chan
    Siu Yuen Chan
    Scientific Reports, 4
  • [47] Therapeutic potential of GluN2B subtype selective NMDA receptor antagonists: Progress and prospects
    Kemp, John A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
  • [48] Comparison of three novel radiotracers for GluN2B-containing NMDA receptors in non-human primates: (R)-[11C]NR2B-Me, (R)-[18F]of-Me-NB1, and (S)-[18F]of-NB1
    Smart, Kelly
    Zheng, Ming-Qiang
    Ahmed, Hazem
    Fang, Hanyi
    Xu, Yuping
    Cai, Lisheng
    Holden, Daniel
    Kapinos, Michael
    Haider, Ahmed
    Felchner, Zachary
    Ropchan, Jim R.
    Tamagnan, Gilles
    Innis, Robert B.
    Pike, Victor W.
    Ametamey, Simon M.
    Huang, Yiyun
    Carson, Richard E.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2022, 42 (08): : 1398 - 1409
  • [49] Synthesis and Pharmacological Evaluation of Enantiomerically Pure GluN2B Selective NMDA Receptor Antagonists
    Boergel, Frederik
    Szermerski, Marina
    Schreiber, Julian A.
    Temme, Louisa
    Strutz-Seebohm, Nathalie
    Lehmkuhl, Kirstin
    Schepmann, Dirk
    Ametamey, Simon M.
    Seebohm, Guiscard
    Schmidt, Thomas J.
    Wuensch, Bernhard
    CHEMMEDCHEM, 2018, 13 (15) : 1580 - 1587
  • [50] Uncoupling DAPK1 from NMDA receptor GluN2B subunit exerts rapid antidepressant-like effects
    S-X Li
    Y Han
    L-Z Xu
    K Yuan
    R-X Zhang
    C-Y Sun
    D-F Xu
    M Yuan
    J-H Deng
    S-Q Meng
    X-J Gao
    Q Wen
    L-J Liu
    W-L Zhu
    Y-X Xue
    M Zhao
    J Shi
    L Lu
    Molecular Psychiatry, 2018, 23 : 597 - 608