Synthesis of vinca alkaloids and related compounds, LXXXVII. Reversed enantioselectivity in different approaches

被引：0
|
作者：
Szabo, L [1 ]
Nagy, T [1 ]
Kalaus, G [1 ]
Szantay, C [1 ]
机构：
[1] Tech Univ Budapest, Inst Organ Chem, H-1521 Budapest, Hungary
来源：
ACH-MODELS IN CHEMISTRY | 1998年 / 135卷 / 04期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Using the same chiral auxiliaries during the enantioselective synthesis of vincamine the absolute configuration depends on the selected approach. Starting from Wenkert enamine the natural (+)-vincamine, while using the reaction sequence through vincadifformine type intermediate, the (-)-enantiomer is formed.
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页码：641 / 651
页数：11
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