A new flavone glycoside from the leaves of Agastache rugosa (Fisch & CAMey.) Kuntze

被引:10
|
作者
Park, SeonJu [1 ]
Kim, Nanyoung [1 ]
Yoo, Guijae [1 ]
Kim, YoonJae [1 ]
Lee, Taek Hwan [1 ]
Kim, Sun Yeou [2 ]
Kim, Seung Hyun [1 ]
机构
[1] Yonsei Univ, Coll Pharm, Yonsei Inst Pharmaceut Sci, Inchon 21983, South Korea
[2] Gachon Univ, Coll Pharm, Inchon 21936, South Korea
基金
新加坡国家研究基金会;
关键词
Agastache rugosa; Lamiaceae; Flavone glycoside; Flavonoid; Phenyl glycoside; Megastigmane glycoside; PHENOLIC-COMPOUNDS; ESSENTIAL OIL; CHEMICAL-CONSTITUENTS; GLUCOSIDES; INHIBITION; SHOOTS; FLOWER;
D O I
10.1016/j.bse.2016.05.019
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Agastache rugosa (Fisch. & C.A.Mey.) Kuntze has been widely used as a food spice and a remedy for colds in Korea, China and Japan. In this study, one new flavone glycoside (1) along with six flavonoids (2-7), nine phenyl glycosides (8-16) and three megastigmane glycosides (17-19) were isolated from the leaves of A. rugosa. By extensive spectroscopic methods including 1D and 2D NMR, and MS data, the structure of the new compound (1) was elucidated as acacetin 7-O-beta-(6 ''-(E)-crotonylglucopyranoside). From present investigation, compound 1 and 7-19 were isolated for the first time from the genus Agastache and 1, 16, 18 and 19 in the Lamiaceae family. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:17 / 21
页数:5
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