Oxidative cross-coupling of pyridine N-oxides and ethers between C(sp2)-H/C(sp3)-H bonds under transition-metal-free conditions

被引：51
|
作者：
Sun, Wei [1 ]
Xie, Zuguang [1 ]
Liu, Jie [1 ]
Wang, Lei [1 ,2 ]
机构：
[1] Huaibei Normal Univ, Dept Chem, Huaibei 235000, Anhui, Peoples R China
[2] Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2015年 / 13卷 / 15期
基金：
美国国家科学基金会;
关键词：
C-H FUNCTIONALIZATION; DIRECT ARYLATION; ALKYLATION; AZOLES; AZINE; HETEROAROMATICS; DISCOVERY; ALCOHOLS; ADJACENT;
D O I：
10.1039/c5ob00237k
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel and efficient method based on the cross-coupling reactions of pyridine N-oxides with ethers between C(sp(2))-H/C(sp(3))-H bonds in the presence of TBHP was developed. The strategy provides an alternative approach to the pyridine moiety under transition-metal-free conditions.
引用
收藏
页码：4596 / 4604
页数：9
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