Anticandidal Activity of the Essential Oil of Nepeta transcaucasica Grossh.

被引：11
|
作者：
Iscan, Gokalp [1 ]
Kose, Y. Bulent [2 ]
Demirci, Betul [1 ]
Baser, K. Husnu Can [1 ,3 ]
机构：
[1] Anadolu Univ, Fac Pharm, Dept Pharmacognosy, TR-26470 Eskisehir, Turkey
[2] Anadolu Univ, Fac Pharm, Dept Pharmaceut Bot, TR-26470 Eskisehir, Turkey
[3] King Saud Univ, Fac Sci, Dept Bot & Microbiol, Riyadh, Saudi Arabia
来源：
CHEMISTRY & BIODIVERSITY | 2011年 / 8卷 / 11期
关键词：
Nepeta transcaucasica; Essential oils; Anticandidal properties; ANTIMICROBIAL ACTIVITY; CONSTITUENTS;
D O I：
10.1002/cbdv.201100091
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Hydrodistallation of the aerial parts of Nepeta transcaucasica Grossh. (Lamiaceae), collected in Agri, Dogubayazit Province, afforded an essential oil that was characterized by GC and GC/MS analyses. Twenty-seven compounds, representing 97.69% of the total oil composition, were identified, and 4aa,7a,7a beta-nepetalactone (1; 39%), 4aa,7a,7aa-nepetalactone (2; 28%), and germacrene D (3; 15%) constituted the major components. The anticandidal effects of the oil were evaluated against seven Candida strains by using the broth microdilution method. The oil showed good inhibitory effects against C. glabrata and C. tropicalis at minimal inhibitory concentrations (MICs) of 0.09 and 0.375 mg/ml, respectively.
引用
收藏
页码：2144 / 2148
页数：5
相关论文
共 50 条
  • [1] Chemical Composition of Essential Oils from Nepeta transcaucasica Grossh. and Nepeta cataria L. Cultivated in Bulgaria and Their Antimicrobial and Antioxidant Activity
    Mollova, Silviya
    Dzhurmanski, Anatoli
    Fidan, Hafize
    Bojilov, Dimitar
    Manolov, Stanimir
    Dincheva, Ivayla
    Stankov, Stanko
    Stoyanova, Albena
    Ercisli, Sezai
    Assouguem, Amine
    Marc, Romina Alina
    Ullah, Riaz
    Bari, Ahmed
    ACS OMEGA, 2023, 8 (17): : 15441 - 15449
  • [2] STUDY OF MONO-TERPENIC PART OF ESSENTIAL OIL NEPETA-TRANSCAUCASICA
    MISHUROVA, SS
    SHIKHIEV, AS
    KHIMIYA PRIRODNYKH SOEDINENII, 1977, (06): : 865 - 866
  • [3] THE OF ESSENTIAL OILS LACTONES OF NEPETA-TRANSCAUCASICA AND NEPETA-SIBIRICA
    KUBRAC, MN
    POPA, DP
    KHIMIYA PRIRODNYKH SOEDINENII, 1980, (03): : 420 - 421
  • [4] Antifungal activity of Nepeta rtanjensis essential oil
    Gribic, Milica Ljaljevic
    Stupar, Milos
    Vukojevic, Jelena
    Sokovic, Marina
    Misic, Danijela
    Grubisic, Dragoljub
    Ristic, Mihailo
    JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2008, 73 (10) : 961 - 965
  • [5] Antimicrobial activity of Nepeta rtanjensis essential oil
    Stojanovic, G
    Radulovic, N
    Lazarevic, J
    Miladinovic, D
    Dokovic, D
    JOURNAL OF ESSENTIAL OIL RESEARCH, 2005, 17 (05) : 587 - 589
  • [6] Herbicidal Activity of Nepeta flavida Essential Oil
    Bozok, Fuat
    JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2018, 21 (06) : 1687 - 1693
  • [7] Nepeta macrosiphon Essential Oil Chemical Composition and Antioxidant Activity
    Mollaei, Saeed
    Holasu, Mohadeseh Abbasi
    BIOMEDICAL AND BIOTECHNOLOGY RESEARCH JOURNAL, 2024, 8 : S35 - S35
  • [8] Constituent Composition and Biological Activity of Nepeta manchuriensis Essential Oil
    P. G. Gorovoi
    E. M. Suleimen
    R. V. Dudkin
    M. Wang
    I. Khan
    S. A. Ross
    Chemistry of Natural Compounds, 2015, 51 : 989 - 990
  • [9] Constituent Composition and Biological Activity of Nepeta manchuriensis Essential Oil
    Gorovoi, P. G.
    Suleimen, E. M.
    Dudkin, R. V.
    Wang, M.
    Khan, I.
    Ross, S. A.
    CHEMISTRY OF NATURAL COMPOUNDS, 2015, 51 (05) : 989 - 990
  • [10] Composition and anticandidal activity of the essential oil of Chaerophyllum byzantinum Boiss.
    Kürkçüoglu, M
    Baser, KHC
    Iscan, G
    Malyer, H
    Kaynak, G
    FLAVOUR AND FRAGRANCE JOURNAL, 2006, 21 (01) : 115 - 117
12345