Hydronephrosis: A View from the Inside

被引：22

作者：

Mesrobian, Hrair-George O. ^{[1
,3
]}

Mirza, Shama P. ^{[2
,3
]}

机构：

[1] Med Coll Wisconsin, Dept Urol, Div Pediat Urol, Milwaukee, WI 53226 USA

[2] Med Coll Wisconsin, Dept Biochem, Milwaukee, WI 53226 USA

[3] Childrens Hosp Wisconsin, Milwaukee, WI 53226 USA

来源：

PEDIATRIC CLINICS OF NORTH AMERICA | 2012年 / 59卷 / 04期

关键词：

Hydronephrosis; Prenatal; Kidney; Evaluation and management; Urinary proteome; URETEROPELVIC JUNCTION OBSTRUCTION; MAGNETIC-RESONANCE UROGRAPHY; URINARY PROTEOME; RENAL-DISEASE; PYELOPLASTY; MECHANISMS; MANAGEMENT; NEWBORN; UPDATE;

D O I：

10.1016/j.pcl.2012.05.008

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Unilateral ureteropelvic junction obstruction (UPJO) is the most common prenatally detected disease leading to hydronephrosis. The obstructive anatomic lesion leads to varying degrees of hydronephrosis, ranging from no apparent effect on renal function to atrophy. Furthermore, the natural course of hydronephrosis varies from spontaneous resolution to progressive deterioration and may take upwards of 3 years for a kidney to declare itself. The objectives of this article are to update our knowledge regarding the evaluation and management of UPJO in depth and to discuss the emerging value of urinary proteome analysis to the clinical arena.

引用

页码：839 / +

页数：14

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