In vivo dosimetry for lung radiotherapy including SBRT

被引:21
|
作者
McCurdy, Boyd M. C. [1 ,2 ,3 ]
McCowan, Peter M. [1 ]
机构
[1] CancerCare Manitoba, Div Med Phys, Winnipeg, MB R3E 0V9, Canada
[2] Univ Manitoba, Dept Phys & Astron, Winnipeg, MB R3M 2N2, Canada
[3] Univ Manitoba, Dept Radiol, Winnipeg, MB R3M 2N2, Canada
关键词
In vivo dosimetry; Dose verification; Treatment verification; Lung SBRT; PORTAL IMAGING DEVICE; MODULATED ARC THERAPY; 3-DIMENSIONAL DOSE RECONSTRUCTION; EPID DOSIMETRY; TREATMENT VERIFICATION; RADIATION-THERAPY; CONVOLUTION MODEL; CANCER PATIENTS; PRETREATMENT VERIFICATION; CLINICAL-EXPERIENCE;
D O I
10.1016/j.ejmp.2017.05.065
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
SBRT for lung cancer is being rapidly adopted as a treatment option in modern radiotherapy centres. This treatment is one of the most complex in common clinical use, requiring significant expertise and resources. It delivers a high dose per fraction (typically similar to 6-30 Gy/fraction) over few fractions. The complexity and high dose delivered in only a few fractions make powerful arguments for the application of in vivo dosimetry methods for these treatments to enhance patient safety. In vivo dosimetry is a group of techniques with a common objective -to estimate the dose delivered to the patient through a direct measurement of the treatment beam(s). In particular, methods employing an electronic portal imaging device have been intensely investigated over the past two decades. Treatment verification using in vivo dosimetry approaches has been shown to identify errors that would have been missed with other common quality assurance methods. With the addition of in vivo dosimetry to verify treatments, medical physicists and clinicians have a higher degree of confidence that the dose has been delivered to the patient as intended. In this review, the technical aspects and challenges of in vivo dosimetry for lung SBRT will be presented, focusing on transit dosimetry applications using electronic portal imaging devices (EPIDs). Currently available solutions will be discussed and published clinical experiences, which are very limited to date, will be highlighted. (C) 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:123 / 130
页数:8
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