Synthesis of imidazole N-oxides in solvent-free conditions

被引:0
|
作者
Alcazar, J [1 ]
Begtrup, M [1 ]
delaHoz, A [1 ]
机构
[1] ROYAL DANISH SCH PHARM,DEPT MED CHEM,DK-2100 COPENHAGEN,DENMARK
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Cyclization of 1,2-diimines with oximes was performed under solvent-free conditions using silica gel and aluminum oxide as supports and catalysts. The reaction proceeded under milder reaction conditions to give imidazole N-oxides. The N-oxides were obtained in higher yields by easier work-up procedure than in the usual reactions performed in solution.
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页码:1465 / 1470
页数:6
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