Antimalarial peroxides in the ginghaosu (artemisinin) and yingzhaosu families

被引：31
|
作者：
Posner, GH [1 ]
机构：
[1] Johns Hopkins Univ, Dept Chem, Baltimore, MD 21218 USA
来源：
EXPERT OPINION ON THERAPEUTIC PATENTS | 1998年 / 8卷 / 11期
基金：
美国国家卫生研究院;
关键词：
chemotherapy; combination therapy; dimers; endoperoxides; malaria; tetraoxanes; trioxanes;
D O I：
10.1517/13543776.8.11.1487
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Recent scientific and patent literature on therapeutically promising antimalarial peroxides is reviewed through to mid-1998. Several of these new chemical entities are efficacious and apparently safe antimalarials. Major industrial support is now needed for development of one or more of these drug candidates.
引用
收藏
页码：1487 / 1493
页数：7
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