Despite the fairly extensive body of research describing nurses' thinking in practice, our understanding of this phenomenon remains incomplete. Until we have a full description of nurses' thinking, the component of our practice that is an exercise in clinical judgment will be less precise and scientific. This descriptive study utilized think aloud method to identify and describe the thinking strategies that nurses use in practice. Findings from this study improve our understanding of nurses' thinking in practice and provide information that can facilitate the development of decision support systems to assist nurses in their practice.