EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology

被引：64
|
作者：
Reche, PA
Zhang, H
Glutting, JP
Reinherz, EL
机构：
[1] Dana Farber Canc Inst, Immunobiol Lab, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA
[3] Harvard Univ, Sch Med, Dept Med, Boston, MA 02115 USA
来源：
BIOINFORMATICS | 2005年 / 21卷 / 09期
关键词：
D O I：
10.1093/bioinformatics/bti269
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens. The EPIMHC database is accessible through a web server that has been designed to facilitate research in computational vaccinology. Importantly, peptides resulting from a query can be selected to derive specific motif-matrices. Subsequently, these motif-matrices can be used in combination with a dynamic algorithm for predicting MHC-binding peptides from user-provided protein queries.
引用
收藏
页码：2140 / 2141
页数：2
相关论文
共 34 条
  • [1] MHCPEP - A DATABASE OF MHC-BINDING PEPTIDES
    BRUSIC, V
    RUDY, G
    HARRISON, LC
    NUCLEIC ACIDS RESEARCH, 1994, 22 (17) : 3663 - 3665
  • [2] MHCPEP, a database of MHC-binding peptides: Update 1996
    Brusic, V
    Rudy, G
    Kyne, AP
    Harrison, LC
    NUCLEIC ACIDS RESEARCH, 1997, 25 (01) : 269 - 271
  • [3] MHCPEP - A database of MHC-binding peptides: Update 1995
    Brusic, V
    Rudy, G
    Kyne, AP
    Harrison, LC
    NUCLEIC ACIDS RESEARCH, 1996, 24 (01) : 242 - 244
  • [4] MHCPEP, a database of MHC-binding peptides: update 1997
    Brusic, V
    Rudy, G
    Harrison, LC
    NUCLEIC ACIDS RESEARCH, 1998, 26 (01) : 368 - 371
  • [5] Predicting sequences and structures of MHC-binding peptides: a computational combinatorial approach
    Jun Zeng
    Herbert R. Treutlein
    George B. Rudy
    Journal of Computer-Aided Molecular Design, 2001, 15 : 573 - 586
  • [6] Predicting sequences and structures of MHC-binding peptides: a computational combinatorial approach
    Zeng, J
    Treutlein, HR
    Rudy, GB
    JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2001, 15 (06) : 573 - 586
  • [7] SVMHC:: a server for prediction of MHC-binding peptides
    Donnes, Pierre
    Kohlbacher, Oliver
    NUCLEIC ACIDS RESEARCH, 2006, 34 : W194 - W197
  • [8] SVRMHC prediction server for MHC-binding peptides
    Wan, Ji
    Liu, Wen
    Xu, Qiqi
    Ren, Yongliang
    Flower, Darren R.
    Li, Tongbin
    BMC BIOINFORMATICS, 2006, 7 (1)
  • [9] SVRMHC prediction server for MHC-binding peptides
    Ji Wan
    Wen Liu
    Qiqi Xu
    Yongliang Ren
    Darren R Flower
    Tongbin Li
    BMC Bioinformatics, 7
  • [10] POSITIVE SELECTION INDUCED BY MHC-BINDING PEPTIDES IN FTOC
    HOGQUIST, KA
    GAVIN, MA
    BEVAN, MJ
    JOURNAL OF IMMUNOLOGY, 1993, 150 (08): : A8 - A8
1234