Diastereoselective synthesis of 2′,3′-dideoxy-β-C-glucopyranosides as intermediates for the synthesis of 2′,3′-dideoxy-β-D-glucopyranosyl-C-nucleosides

被引：4

作者：

Loepfe, Michael ^{[1
]}

Siegel, Jay S. ^{[1
]}

机构：

[1] Univ Zurich, Inst Organ Chem, CH-8057 Zurich, Switzerland

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2007年 / 26卷 / 8-9期

关键词：

C-glycosides; C-nucleosides;

D O I：

10.1080/15257770701508695

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An extension of the Vorbruggen method of nucleotide synthesis for the synthesis of G glucopyranosides, as intermediates for C-nucleosides, is described. It could be shown that the diastereoselectivity of the reaction can be tuned by a simple change of protecting groups.

引用

页码：1029 / 1035

页数：7

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