Enantiomeric enrichment of α-amino acid derivatives:: recrystallization of N-Fmoc α-amino acid tert-butyl esters

被引：22
|
作者：
O'Donnell, MJ [1 ]
Delgado, F [1 ]
机构：
[1] Indiana Univ Purdue Univ, Dept Chem, Indianapolis, IN 46202 USA
来源：
TETRAHEDRON | 2001年 / 57卷 / 30期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/S0040-4020(01)00554-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The optical purity of products derived from enantioselective reactions of the benzophenone imine of glycine tert-butyl esters can often be improved by conversion to the N-Fmoc alpha -amino acid tert-butyl esters followed by simple recrystallization. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：6641 / 6650
页数：10
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