Development of a Stable Helper Virus-Free Producer Cell Line for Scalable Adeno-Associated Virus Vectors Production Based on Human Suspension Cells

被引:0
|
作者
Goncalves, Ines do Carmo [1 ]
Hein, Kerstin [1 ]
Hudjetz, Ben [1 ]
Strempel, Nikola [1 ]
Riebesehl, Nina [1 ]
Kewes, Helmut [1 ]
Bauer, Thu [1 ]
Jamaladin, Israa [1 ]
Bialek, Corinna [1 ]
Schmidt-Hertel, Sabine [1 ]
Coronel, Juliana [1 ]
Patil, Aishwarya [1 ]
Al-Dali, Ahmad [1 ]
Faust, Nicole [1 ]
Wissing, Silke [1 ]
机构
[1] CEVEC Pharmaceut, Viral Vectors, Cologne, Germany
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
454
引用
收藏
页码:201 / 202
页数:2
相关论文
共 50 条
  • [21] Establishment of a Novel Cell Line for the Enhanced Production of Recombinant Adeno-Associated Virus Vectors for Gene Therapy
    Satkunanathan, Stifani
    Wheeler, Jun
    Thorpe, Robin
    Zhao, Yuan
    HUMAN GENE THERAPY, 2014, 25 (11) : 929 - 941
  • [22] Production of recombinant adeno-associated virus vectors using a packaging cell line and a hybrid recombinant adenovirus
    X L Liu
    K R Clark
    P R Johnson
    Gene Therapy, 1999, 6 : 293 - 299
  • [23] Gene targeting in human pluripotent stem cells with adeno-associated virus vectors
    Mitsui, Kaoru
    Suzuki, Keiichiro
    Aizawa, Emi
    Kawase, Eihachiro
    Suemori, Hirofumi
    Nakatsuji, Norio
    Mitani, Kohnosuke
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 388 (04) : 711 - 717
  • [24] Production methods for gene transfer vectors based on adeno-associated virus serotypes
    Grimm, D
    METHODS, 2002, 28 (02) : 146 - 157
  • [25] Production, Purification, and Quality Control for Adeno-associated Virus-based Vectors
    Fripont, Shelly
    Marneffe, Catherine
    Marino, Marika
    Rincon, Melvin Y.
    Holt, Matthew G.
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2019, (143):
  • [26] Establishing a clone selection strategy to accelerate recombinant adeno-associated virus (rAAV) producer cell line development
    Richards, N.
    Eastham, A.
    Tiernan, A.
    Borowy, V.
    Clark, K. R.
    Wadsworth, S. C.
    Tipper, C.
    Jing, Y.
    HUMAN GENE THERAPY, 2016, 27 (11) : A158 - A158
  • [27] Scalable platform for production of recombinant adeno-associated viral vectors in suspension HEK293 cells
    Chippendale, T.
    Silvano, M.
    Krakowiak, J.
    Hassall, A.
    Wong, A.
    Tam, L.
    Liu, Q.
    Payne, T.
    HUMAN GENE THERAPY, 2019, 30 (08) : A22 - A22
  • [28] Establishment of a Clonal, Serum-Free, Suspension-Adapted HEK293 Cell Line for the Manufacturing of Adeno-Associated Virus Vectors
    Campbell, Marguerite
    Geosits, Kelly
    Ercolino, Matthew
    Burton, Thomas J.
    Ngan Trinh
    Umaer, Khan
    Tummala, Srivanya
    Sacks, Amy
    Tomkowicz, Brian
    MOLECULAR THERAPY, 2023, 31 (04) : 494 - 494
  • [29] Adeno-associated virus perfusion enhanced expression: A commercially scalable, high titer, high quality producer cell line process
    Xue, Wei
    Fulco, Cameron
    Sha, Sha
    Alden, Nick
    Panteli, Jan
    Hossler, Patrick
    Warren, James
    MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT, 2024, 32 (02)
  • [30] Development of a Novel Recombinant Adeno-Associated Virus Production System Using Human Bocavirus 1 Helper Genes
    Wang, Zekun
    Cheng, Fang
    Engelhardt, John F.
    Yan, Ziying
    Qiu, Jianming
    MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2018, 11 : 40 - 51