Investigating pharmacology profiles of TLR7 agonists in a mouse model of lymphopenia

被引:0
|
作者
Perkins, H. [1 ]
Khodai, T. [1 ]
Mechiche, H. [1 ]
Colman, P. [1 ]
Burden, F. [1 ]
Laxton, C. [1 ]
Horscroft, N. [1 ]
Corey, T. [1 ]
Rodrigues, D. [1 ]
Rawal, J. [1 ]
Webster, R. [1 ]
Heyen, J. [2 ]
Westby, M. [1 ]
Bright, H. [1 ]
机构
[1] Pfizer, Sandwich, Kent, England
[2] Pfizer, San Diego, CA USA
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:84 / 84
页数:1
相关论文
共 50 条
  • [31] TLR7 triggered lymphopenia does not influence susceptibility to post-influenza pneumococcal infection
    Stegemann, S.
    Dahlberg, S.
    Bruder, D.
    Henriques-Normark, B.
    Gunzer, M.
    WIENER KLINISCHE WOCHENSCHRIFT, 2008, 120 : 148 - 149
  • [32] Incorporation of phosphonate into benzonaphthyridine TLR7 agonists for adsorption onto aluminum hydroxide
    Wu, Tom
    Cortez, Alex
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 251
  • [33] Small Molecule TLR7 and 8 Agonists for Treatment of Viral Infection and Cancer
    Tomai, Mark A.
    INFLAMMATION RESEARCH, 2005, 54 : S107 - S107
  • [34] TLR7/8 agonists enhance FcγR in CLL patient monocytes
    Elavazhagan, Saranya
    Shah, Prexy
    Fatehchand, Kavin
    Patel, Hemal
    Cheney, Carolyn
    Muthusamy, Natarajan
    Vasilakos, John
    Matthews, Maura-Ann
    Dietsch, Gregory
    Hershberg, Robert
    Byrd, John
    Tridandapani, Susheela
    Butchar, Jonathan
    JOURNAL OF IMMUNOLOGY, 2014, 192
  • [35] Comparison of the neuroinflammatory pathways induced by TLR7, TLR8 and TLR9 agonists in the neonatal brain
    Butchi, Niranjan Babu
    Pourciau, Susan
    Du, Min
    Morgan, Timothy
    Peterson, Karin
    FASEB JOURNAL, 2008, 22
  • [36] TLR7/TLR8 activation and susceptibility genes synergize to breach gut barrier in a mouse model of lupus
    Ma, Longhuan
    Terrell, Morgan
    Brown, Josephine
    Garcia, Abigail Castellanos
    Elshikha, Ahmed
    Morel, Laurence
    FRONTIERS IN IMMUNOLOGY, 2023, 14
  • [37] Stimulation of Innate Immune Cells by Light-Activated TLR7/8 Agonists
    Ryu, Keun Ah
    Stutts, Lalisa
    Tom, Janine K.
    Mancini, Rock J.
    Esser-Kahn, Aaron P.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 136 (31) : 10823 - 10825
  • [38] Microglia activation in rat spinal cord by systemic injection of TLR3 and TLR7/8 agonists
    Zhang, ZR
    Trautmann, K
    Schluesener, HJ
    JOURNAL OF NEUROIMMUNOLOGY, 2005, 164 (1-2) : 154 - 160
  • [39] TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation
    Larange, Alexandre
    Antonios, Diane
    Pallardy, Marc
    Kerdine-Roemer, Saadia
    JOURNAL OF LEUKOCYTE BIOLOGY, 2009, 85 (04) : 673 - 683
  • [40] Mycobacterium tuberculosis and TLR2 agonists inhibit induction of type I IFN by TLR7/9
    Liu, Yi
    Simmons, Daimon
    Li, Xiaoxia
    Abbott, Derek
    Boom, W.
    Harding, Clifford
    JOURNAL OF IMMUNOLOGY, 2011, 186