Laterally spreading tumors in the colon and rectum

被引:34
|
作者
Lambert, Rene [1 ]
Tanaka, Shinji [2 ]
机构
[1] Int Agcy Res Canc, Screening Grp, F-69372 Lyon 08, France
[2] Hiroshima Univ Hosp, Dept Endoscopy, Hiroshima, Japan
关键词
cancer; colon; endoscopy; laterally spreading tumor; rectum; ENDOSCOPIC SUBMUCOSAL DISSECTION; BAND IMAGING MAGNIFICATION; K-RAS MUTATIONS; COLORECTAL TUMORS; MUCOSAL RESECTION; SERRATED ADENOMA; LARGE SESSILE; POLYPS; EMR; COLONOSCOPY;
D O I
10.1097/MEG.0b013e328355e2d9
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The large and relatively flat colorectal neoplastic lesions called laterally spreading tumors are classified as nonpolypoid despite some mixed patterns with protruding nodules. Large hyperplastic polyps and sessile serrated lesions are non-neoplastic lesions that also have this morphology and may potentially progress to neoplasia. All these large and relatively flat lesions are more frequent in the proximal colon and less conspicuous than polypoid lesions. Their underdiagnosis is a major factor in the failure of colonoscopy to prevent cancer in the proximal colon. The treatment of laterally spreading tumors by endoscopic resection (endoscopic mucosal resection, piecemeal endoscopic mucosal resection, endoscopic submucosal dissection), or by surgery is based on a careful morphologic analysis, taking into account the size and surface with nodules or depression. The technique of endoscopic submucosal dissection should be diffused because it reduces the number of surgical indications. Eur J Gastroenterol Hepatol 24:1123-1134 (C) 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins.
引用
收藏
页码:1123 / 1134
页数:12
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