Pseudoesters and derivatives .35. Reactions of 4-substituted-5-(ethylthio)furan-2(5H)-ones anions with alkylating agents

被引：1
|
作者：
Farina, F [1 ]
Martin, MV [1 ]
deGuerenu, AM [1 ]
机构：
[1] CSIC, INST QUIM ORGAN GEN, E-28006 MADRID, SPAIN
来源：
SYNTHETIC COMMUNICATIONS | 1996年 / 26卷 / 13期
关键词：
D O I：
10.1080/00397919608004570
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Alkylation of anions derived from 5-ethylthio-4-substituted furanones (1-3) is described. The regioselectivity depends on the alkylating agent but mainly on the nature of the substituent. The alkylation of 4-methoxyfuranone 3 proceeds regioselectively to afford the 5-alkylated derivative as sole product.
引用
收藏
页码：2573 / 2586
页数：14
相关论文
共 50 条
  • [21] Synthesis of condensed isoxazolines and isoxazolidines via cycloaddition to furan-2(5H)-ones
    Garcia Ruano, Jose L.
    Fajardo, Cristina
    Fraile, Alberto
    Rosario Martin, M.
    Soriano, Jose F.
    ARKIVOC, 2010, : 303 - 318
  • [22] Enantio selective hydrogenation of 4-(hydroxymethyl) furan-2(5H)-one derivatives
    Bronze-Uhle, Erika Soares
    de Sairre, Mirela Ines
    Donate, Paulo Marcos
    Frederico, Daniel
    JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2006, 259 (1-2) : 103 - 107
  • [23] Capture of CO2 in air for 4,5-disubstituted furan-2(5H)-ones
    Cui, Fei-Hu
    Su, Shi-Xia
    Xu, Yan-li
    Liang, Ying
    Wang, Heng-shan
    Pan, Ying-Ming
    ORGANIC CHEMISTRY FRONTIERS, 2016, 3 (10): : 1304 - 1308
  • [24] Pseudoesters and derivatives .36. Reactions of enolates of 5-ethylthiofuran-2(5H)-ones with aromatic aldehydes: A synthesis of losigamone
    Martin, MR
    Martin, MV
    deGuerenu, AM
    Ortego, JL
    HETEROCYCLES, 1996, 43 (01) : 191 - 198
  • [25] Synthesis of some substituted furan-2(5H)-ones and derived quinoxalinones as potential anti-microbial and anti-cancer agents
    El-Tombary, Alaa A.
    Abdel-Ghany, Yasser S.
    Belal, Ahmad S. F.
    El-Dine, Shams A. Shams
    Soliman, Farid S. G.
    MEDICINAL CHEMISTRY RESEARCH, 2011, 20 (07) : 865 - 876
  • [26] Synthesis of some substituted furan-2(5H)-ones and derived quinoxalinones as potential anti-microbial and anti-cancer agents
    Alaa A. El-Tombary
    Yasser S. Abdel-Ghany
    Ahmad S. F. Belal
    Shams A. Shams El-Dine
    Farid S. G. Soliman
    Medicinal Chemistry Research, 2011, 20 : 865 - 876
  • [27] SnO nanoparticles: a robust and reusable heterogeneous catalyst for the synthesis of 3,4,5-substituted furan-2(5H)-ones
    Javad Safaei-Ghomi
    Elham Heidari-Baghbahadorani
    Hossein Shahbazi-Alavi
    Monatshefte für Chemie - Chemical Monthly, 2015, 146 : 181 - 186
  • [28] Facile and efficient synthesis of 3,4,5-substituted furan-2(5H)-ones by using β-cyclodextrin as reusable catalyst
    Murthy, S. Narayana
    Madhav, B.
    Kumar, A. Vijay
    Rao, K. Rama
    Nageswar, Y. V. D.
    TETRAHEDRON, 2009, 65 (27) : 5251 - 5256
  • [29] SnO nanoparticles: a robust and reusable heterogeneous catalyst for the synthesis of 3,4,5-substituted furan-2(5H)-ones
    Safaei-Ghomi, Javad
    Heidari-Baghbahadorani, Elham
    Shahbazi-Alavi, Hossein
    MONATSHEFTE FUR CHEMIE, 2015, 146 (01): : 181 - 186
  • [30] Synthesis of 3,4,5-substituted furan-2(5H)-ones using Al-doped ZnO nanostructure
    Ghashang, Majid
    Janghorban, Sadaf
    Roudbaraki, Seyyed Jalal
    RESEARCH ON CHEMICAL INTERMEDIATES, 2018, 44 (09) : 5013 - 5029
12345