Defining the biological responses of IL-6 by the study of a novel IL-6 receptor chain immunodeficiency

被引：25
|
作者：
Nahum, Amit [1 ,2 ,3 ]
Sharfe, Nigel [7 ,8 ,9 ,10 ]
Broides, Arnon [2 ]
Dadi, Harjit [7 ,8 ,9 ,10 ]
Naghdi, Zahra [7 ,8 ,9 ,10 ]
Mandola, Amarilla B. [1 ,7 ,8 ,9 ,10 ]
Vong, Linda [7 ,8 ,9 ,10 ]
Arbiv, Adi [3 ]
Dalal, Ilan [11 ,12 ]
Brami, Ido [4 ]
Wormser, Ohad [5 ,6 ]
Levy, Jacov [2 ]
Roifman, Chaim M. [7 ,8 ,9 ,10 ]
机构：
[1] Soroka Univ, Med Ctr, Pediat Dept A, Beer Sheva, Israel
[2] Soroka Univ, Med Ctr, Immunol Clin, Beer Sheva, Israel
[3] Ben Gurion Univ Negev, Primary Immunodeficiency Res Lab, Fac Hlth Sci, Beer Sheva, Israel
[4] Ben Gurion Univ Negev, Dept Clin Biochem, Fac Hlth Sci, Beer Sheva, Israel
[5] Ben Gurion Univ Negev, Morris Kahn Lab Human Genet, Natl Inst Biotechnol Negev, Beer Sheva, Israel
[6] Ben Gurion Univ Negev, Fac Hlth Sci, Beer Sheva, Israel
[7] Univ Toronto, Canadian Ctr Primary Immunodeficiency, Toronto, ON, Canada
[8] Univ Toronto, Jeffrey Modell Res Lab Diag Primary Immunodeficie, Toronto, ON, Canada
[9] Univ Toronto, Dept Paediat, Hosp Sick Children, Div Immunol & Allergy, Toronto, ON, Canada
[10] Univ Toronto, Toronto, ON, Canada
[11] E Wolfson Med Ctr, Dept Pediat, Holon, Israel
[12] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel
来源：
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2020年 / 145卷 / 03期
基金：
加拿大创新基金会;
关键词：
PHOSPHORYLCHOLINE;
D O I：
10.1016/j.jaci.2019.11.015
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
[No abstract available]
引用
收藏
页码：1011 / +
页数：12
相关论文
共 50 条
  • [31] Prevention of neuron and oligodendrocyte degeneration by interleukin-6 (IL-6) and IL-6 receptor/IL-6 fusion protein in organotypic hippocampal slices
    Pizzi, M
    Sarnico, I
    Boroni, F
    Benarese, M
    Dreano, M
    Garotta, G
    Valerio, A
    Spano, PF
    MOLECULAR AND CELLULAR NEUROSCIENCE, 2004, 25 (02) : 301 - 311
  • [32] IL-6 and type 1 diabetes mellitus: T cell responses and increase in IL-6 receptor surface expression
    Gomes, Karina Braga
    ANNALS OF TRANSLATIONAL MEDICINE, 2017, 5 (01)
  • [33] Association of plasma IL-6 and soluble IL-6 receptor levels with the Asp358Ala polymorphism of the IL-6 receptor gene in schizophrenic patients
    Sasayama, Daimei
    Wakabayashi, Chisato
    Hori, Hiroaki
    Teraishi, Toshiya
    Hattori, Kotaro
    Ota, Miho
    Ishikawa, Masanori
    Arima, Kunimasa
    Higuchi, Teruhiko
    Amano, Naoji
    Kunugi, Hiroshi
    JOURNAL OF PSYCHIATRIC RESEARCH, 2011, 45 (11) : 1439 - 1444
  • [34] HUMAN ENDOTHELIAL-CELLS PRODUCE IL-6 - LACK OF RESPONSES TO EXOGENOUS IL-6
    PODOR, TJ
    JIRIK, FR
    LOSKUTOFF, DJ
    CARSON, DA
    LOTZ, M
    REGULATION OF THE ACUTE PHASE AND IMMUNE RESPONSES : INTERLEUKIN-6, 1989, 557 : 374 - 387
  • [35] HUMAN ENDOTHELIAL-CELLS PRODUCE IL-6 - LACK OF RESPONSES TO EXOGENOUS IL-6
    PODOR, TJ
    JIRIK, FR
    LOSKUTOFF, DJ
    CARSON, DA
    LOTZ, M
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1989, 557 : 374 - 387
  • [36] Novel insights and therapeutic approaches into blocking the IL-6/IL-6 receptor pathway after pig organ xenotransplantation
    Hara, Hidetaka
    Zhang, Guoqiang
    Iwase, Hayato
    Yamamoto, Takayuki
    Ayares, David
    Eckhoff, Davin E.
    Cooper, David K. C.
    XENOTRANSPLANTATION, 2019, 26 (05)
  • [37] Novel Insights into Blocking the IL-6 / IL-6 Receptor Pathway after Pig Kidney Xenotransplantation in Baboons.
    Hara, H.
    Zhang, G.
    Iwase, H.
    Yamamoto, T.
    Ayares, D.
    Eckhoff, D. E.
    Cooper, D. K.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2019, 19 : 1053 - 1053
  • [38] Chimeric molecule IL-6/soluble IL-6 receptor is a potent mitogen for fetal hepatocytes
    Zvibel, I
    Brill, S
    Kariv, R
    Traister, A
    Golan, T
    Chebath, J
    Halpern, Z
    Revel, M
    Oren, R
    JOURNAL OF CELLULAR PHYSIOLOGY, 2004, 200 (02) : 245 - 252
  • [39] IL-6 receptor independent stimulation of human gp130 by viral IL-6
    Müllberg, J
    Geib, T
    Jostock, T
    Hoischen, SH
    Vollmer, P
    Voltz, N
    Heinz, D
    Galle, PR
    Klouche, M
    Rose-John, S
    JOURNAL OF IMMUNOLOGY, 2000, 164 (09): : 4672 - 4677
  • [40] The role of soluble IL-6 receptor in mediating the effects of IL-6 on collagenolytic activity.
    Irwin, CR
    Myrillas, TT
    Traynor, P
    Leadbetter, N
    Cawston, T
    JOURNAL OF DENTAL RESEARCH, 2002, 81 : A124 - A124
12345