Autoimmune hypopituitarism in patients with coeliac disease:: Symptoms confusingly similar

被引:25
|
作者
Collin, P [1 ]
Hakanen, M
Salmi, J
Mäki, M
Kaukinen, K
机构
[1] Univ Tampere, Sch Med, FIN-33014 Tampere, Finland
[2] Tampere Univ Hosp, Dept Med, Tampere, Finland
[3] Tampere Univ Hosp, Dept Paediat, Tampere, Finland
[4] Univ Tampere, Inst Med Technol, FIN-33014 Tampere, Finland
关键词
autoimmune hypopituitarism; coeliac disease; gluten-free diet;
D O I
10.1080/003655201750153511
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Coeliac disease does not always respond properly to a gluten-free diet, and treatment may be complicated by an underlying autoimmune endocrine disorder. We report three cases of hypopituitarism in patients with coeliac disease who seemed to have incomplete dietary response. The first patient had diabetes and suffered from hypoglygaemic events: the second had muscular atrophy of unknown origin while the third had growth failure. None had a pituitary mass, suggesting that hypopituitarism was of autoimmune origin. Overall condition improved only after replacement therapy for the underlying hormone deficiency: this association should thus be recognized.
引用
收藏
页码:558 / 560
页数:3
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