An in vitro study of the activity of 10 oral agents against 153 pediatric isolates of Streptococcus pneumoniae identified moxifloxacin and levofloxacin as the most active agents regardless of penicillin or macrolide susceptibility. Moxifloxacin inhibited all strains at 0.25 mug/ml and was 8- to 16-fold more potent than levofloxacin. (C) 2001 Elsevier Science inc. All rights reserved.
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Emory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA
Ctr Dis Control & Prevent, Atlanta, GA USAEmory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA
Mcgee, Lesley
Biek, Donald
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Cerexa Inc, Alameda, CA USAEmory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA
Biek, Donald
Ge, Yigong
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Cerexa Inc, Alameda, CA USAEmory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA
Ge, Yigong
Klugman, Magderie
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机构:Emory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA
Klugman, Magderie
du Plessis, Mignon
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Natl Inst Communicable Dis, Johannesburg, South AfricaEmory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA
du Plessis, Mignon
Smith, Anthony M.
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Natl Inst Communicable Dis, Johannesburg, South AfricaEmory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA
Smith, Anthony M.
Beall, Bernard
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Ctr Dis Control & Prevent, Atlanta, GA USAEmory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA
Beall, Bernard
Whitney, Cynthia G.
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Ctr Dis Control & Prevent, Atlanta, GA USAEmory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA
Whitney, Cynthia G.
Klugman, Keith P.
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机构:Emory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA
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Univ Iowa, Coll Med, Dept Pathol, Div Med Microbiol,Clin Microbiol Labs, Iowa City, IA 52242 USAUniv Iowa, Coll Med, Dept Pathol, Div Med Microbiol,Clin Microbiol Labs, Iowa City, IA 52242 USA