Non-biomimetic oxidation of 1,4-dihydropyridines

被引:12
|
作者
Lavilla, R [1 ]
Gullon, F [1 ]
Baron, X [1 ]
Bosch, J [1 ]
机构
[1] UNIV BARCELONA,FAC PHARM,ORGAN CHEM LAB,E-08028 BARCELONA,SPAIN
关键词
D O I
10.1039/a606919c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The reaction between N-alkyl-1,4-dihydropyridines and dimethyldioxirane leads to dimeric tetrahydropyridines having oxygen atoms at the 2- and 3-positions in good yields and with good stereocontrol; these compounds are useful iminium ion precursors, and are satisfactorily transformed into 2-substituted 3-hydroxy-1,2,3,4-tetrahydropyridines.
引用
收藏
页码:213 / 214
页数:2
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