Induction of apoptosis by the p14ARF tumour suppressor is fully independent of p53 and involves non-mitochondrial death pathways in colorectal cancer

被引:0
|
作者
Overkamp, T. [1 ,2 ]
Mueer, A. [1 ,2 ]
Gillissen, B. [1 ,2 ]
Wendt, J. [1 ,2 ]
Doerken, B. [3 ]
Daniel, P. [1 ,2 ,3 ]
Hemmati, P. [1 ,2 ,3 ]
机构
[1] Charite, Expt & Clin Res Ctr, D-13353 Berlin, Germany
[2] Max Delbruck Ctr Mol Med, Berlin, Germany
[3] Charite, Med Klin mS Hamatol & Onkol, D-13353 Berlin, Germany
来源
ONKOLOGIE | 2010年 / 33卷
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:225 / 225
页数:1
相关论文
共 50 条
  • [11] p14ARF upregulation of p53 and enhanced effects of 5-fluorouracil in pancreatic cancer
    Zhang, QH
    Ni, QX
    Gan, J
    Shen, ZZ
    Luo, JM
    Jin, C
    Zhang, N
    Zhang, YL
    CHINESE MEDICAL JOURNAL, 2003, 116 (08) : 1150 - 1155
  • [12] p14ARF upregulation of p53 and enhanced effects of 5-fluorouracil in pancreatic cancer
    张群华
    倪泉兴
    甘军
    沈兆忠
    罗建民
    金忱
    张妞
    张延龄
    Chinese Medical Journal, 2003, (08)
  • [13] Oncomir miR-125b Suppresses p14ARF to Modulate p53-Dependent and p53-Independent Apoptosis in Prostate Cancer
    Amir, Sumaira
    Ma, Ai-Hong
    Shi, Xu-Bao
    Xue, Lingru
    Kung, Hsing-Jien
    White, Ralph W. deVere
    PLOS ONE, 2013, 8 (04):
  • [14] Deregulation of the tumour suppressor genes p14ARF, p15INK4b, p16INK4a and p53 in basal cell carcinoma
    Kanellou, P.
    Zaravinos, A.
    Zioga, M.
    Spandidos, D. A.
    BRITISH JOURNAL OF DERMATOLOGY, 2009, 160 (06) : 1215 - 1221
  • [15] Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14ARF tumor suppressor genes
    Edwards, SJ
    Dix, BR
    Myers, CJ
    Dobson-Le, D
    Huschtscha, L
    Hibma, M
    Royds, J
    Braithwaite, AW
    JOURNAL OF VIROLOGY, 2002, 76 (24) : 12483 - 12490
  • [16] Frequent alteration of p16INK4a/p14ARF and p53 pathways in the round cell component of myxoid/round cell liposarcoma:: p53 gene alterations and reduced p14ARF expression both correlate with poor prognosis
    Oda, Y
    Yamamoto, H
    Takahira, T
    Kobayashi, C
    Kawaguchi, K
    Tateishi, N
    Nozuka, Y
    Tamiya, S
    Tanaka, K
    Matsuda, S
    Yokoyama, R
    Iwamoto, Y
    Tsuneyoshi, M
    JOURNAL OF PATHOLOGY, 2005, 207 (04): : 410 - 421
  • [17] p14ARF sensitizes human osteosarcoma cells to cisplatin-induced apoptosis in a p53-independent manner
    Yuan, Xiang-Wei
    Zhu, Xiao-Feng
    Huang, Xiu-Fang
    Sheng, Pu-Yi
    He, Ai-Shan
    Yang, Zi-Bo
    Deng, Rong
    Feng, Gong-Kan
    Liao, Wei-Ming
    CANCER BIOLOGY & THERAPY, 2007, 6 (07) : 1074 - 1080
  • [18] Inhibition of p63 transcriptional activity by p14ARF:: Functional and physical link between human ARF tumor suppressor and a member of the p53 family
    Calabrò, V
    Mansueto, G
    Santoro, R
    Gentilella, A
    Pollice, A
    Ghioni, P
    Guerrini, L
    La Mantia, G
    MOLECULAR AND CELLULAR BIOLOGY, 2004, 24 (19) : 8529 - 8540
  • [19] A novel p53-independent function for p14ARF, the regulation of angiogenesis via induction of TIMP3
    Zerrouqi, Abdessamad
    Pyrzynska, Beata
    Brat, Daniel
    Van Meir, Erwin G.
    NEURO-ONCOLOGY, 2006, 8 (04) : 394 - 394
  • [20] Pokemon enhances proliferation, cell cycle progression and anti-apoptosis activity of colorectal cancer independently of p14ARF–MDM2–p53 pathway
    Yi Zhao
    Yun-hong Yao
    Li Li
    Wei-fang An
    Hong-zen Chen
    Li-ping Sun
    Hai-xian Kang
    Sen Wang
    Xin-rong Hu
    Medical Oncology, 2014, 31