Taxanes in the Treatment of Advanced Gastric Cancer

被引：16
|
作者：
Kang, Byung Woog [1 ]
Kwon, Oh-Kyoung [2 ]
Chung, Ho Young [2 ]
Yu, Wansik [2 ]
Kim, Jong Gwang [1 ]
机构：
[1] Kyungpook Natl Univ, Dept Oncol Hematol, Med Ctr, Sch Med,Canc Res Inst, 807 Hogukno, Daegu 41404, South Korea
[2] Kyungpook Natl Univ, Dept Surg, Kyungpook Natl Univ Hosp, Sch Med, Daegu 41494, South Korea
来源：
MOLECULES | 2016年 / 21卷 / 05期
基金：
新加坡国家研究基金会;
关键词：
gastric cancer; taxanes; paclitaxel; docetaxel; chemotherapy; PHASE-III TRIAL; ALBUMIN-BOUND PACLITAXEL; 2ND-LINE CHEMOTHERAPY; 1ST-LINE THERAPY; PLUS CISPLATIN; ANTITUMOR-ACTIVITY; OPEN-LABEL; FLUOROURACIL; DOCETAXEL; ADENOCARCINOMA;
D O I：
10.3390/molecules21050651
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Although rapid advances in treatment options have improved the prognosis of advanced gastric cancer (AGC), it remains a major public health problem and the second leading cause of cancer-related deaths in the world. Taxanes (paclitaxel and docetaxel) are microtubule stabilizing agents that inhibit the process of cell division, and have shown antitumor activity in the treatment of AGC as a single or combination chemotherapy. Accordingly, this review focuses on the efficacy and tolerability of taxanes in the first-or second-line chemotherapy setting for AGC.
引用
收藏
页数：10
相关论文
共 50 条
  • [21] SURVIVAL BENEFIT ASSOCIATED WITH FLUOROPYRIMIDINES, PLATINUM AGENTS, TAXANES, AND IRINOTECAN DURING ALL LINES OF TREATMENT IN PATIENTS WITH ADVANCED GASTRIC CANCER
    Shitara, K.
    Matsuo, K.
    Takahari, D.
    Yokota, T.
    Ura, T.
    Ito, S.
    Sawaki, A.
    Tajika, M.
    Kawai, H.
    Muro, K.
    ANNALS OF ONCOLOGY, 2010, 21 : 228 - 229
  • [22] Progress in the treatment of advanced gastric cancer
    Song, Zheyu
    Wu, Yuanyu
    Yang, Jiebing
    Yang, Dingquan
    Fang, Xuedong
    TUMOR BIOLOGY, 2017, 39 (07)
  • [23] Taxanes in ovarian cancer treatment
    Seetalarom, K
    Kudelka, AP
    Verschraegen, CF
    Kavanagh, JJ
    CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, 1997, 9 (01) : 14 - 20
  • [24] Vinorelbine combined with cisplatin in the treatment of advanced breast cancer failed to anthracyclines and/or taxanes
    Shen, G
    Jiang, Z
    Song, S
    BREAST CANCER RESEARCH AND TREATMENT, 2003, 82 : S87 - S87
  • [25] Pharmacoeconomic profile of taxanes in advanced ovarian cancer
    Messori, A
    Trippoli, S
    ANTI-CANCER DRUGS, 1998, 9 (10) : 909 - 916
  • [26] Advances in Treatment Models of Advanced Gastric Cancer
    Li, Tao
    He, Yufang
    Zhong, Qinglei
    Yu, Jiang
    Chen, Xinhua
    TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 2022, 21
  • [27] Multimodal treatment in locally advanced gastric cancer
    Goetze, Oliver Thorsten
    Al-Batran, Salah-Eddin
    Chevallay, Mickael
    Moenig, Stefan Paul
    UPDATES IN SURGERY, 2018, 70 (02) : 173 - 179
  • [28] Drug treatment for advanced/metastatic gastric cancer
    Masetti, Michael
    Scheck, Magdalena K.
    Lorenzen, Sylvie
    GASTROENTEROLOGIE, 2023, 18 (03): : 205 - 213
  • [29] Current questions for the treatment of advanced gastric cancer
    Cervantes, A.
    Roda, D.
    Tarazona, N.
    Rosello, S.
    Perez-Fidalgo, J. A.
    CANCER TREATMENT REVIEWS, 2013, 39 (01) : 60 - 67
  • [30] Multimodal treatment in locally advanced gastric cancer
    Oliver Thorsten Goetze
    Salah-Eddin Al-Batran
    Mickael Chevallay
    Stefan Paul Mönig
    Updates in Surgery, 2018, 70 : 173 - 179
12345