ADVERSE EVENTS ASSOCIATED WITH mTOR INHIBITION: RESULTS FROM THE A2310 STUDY COMPARING EVEROLIMUS AND MMF IN DE NOVO HEART TRANSPLANT RECIPIENTS

被引:0
|
作者
Poncelet, A. [1 ]
Musumeci, F. [2 ]
Fuchs, U. [3 ]
Mattei, M. F. [4 ]
Dong, G. [5 ]
Lopez, P. [6 ]
Hirt, S. [7 ]
机构
[1] Catholic Univ Louvain, Fac Med, B-1200 Brussels, Belgium
[2] S Camillo Forlanini Hosp, Dept Cardiovasc Sci, Rome, Italy
[3] Ruhr Univ Bochum, Heart Ctr N Rhine Westphalia, Univ Hosp, Bad Oeynhausen, Germany
[4] Hop Brabois, Dept Cardiol & Transplantat, Nancy, France
[5] Novartis Pharmaceut, Dev, E Hanover, NJ USA
[6] Novartis Pharma AG, Clin Dev, Basel, Switzerland
[7] Univ Med Ctr Regensburg, Dept Cardiothorac Surg, Regensburg, Germany
关键词
D O I
暂无
中图分类号
R61 [外科手术学];
学科分类号
摘要
引用
收藏
页码:58 / 58
页数:1
相关论文
共 50 条
  • [21] A PROSPECTIVE CLINICAL TRIAL COMPARING TACROLIMUS-MMF TO CYCLOSPORINE-EVEROLIMUS IN DE NOVO RENAL TRANSPLANT RECIPIENTS: 2 YEARS RESULTS
    Favi, Evaldo
    Citterio, Franco
    Spagnoletti, Gionata
    Gargiulo, Antonio
    Romagnoli, Jacopo
    Castagneto, Marco
    TRANSPLANT INTERNATIONAL, 2009, 22 : 241 - 241
  • [22] mTOR-Inhibitor-Attributed Events: Review of 2-Year Safety Data in Heart Transplant Recipients Receiving Everolimus Vs MMF in the Randomised Multi-Centre 2310 Study
    Rinaldi, M.
    Wang, S. S.
    Hirt, S.
    Eisen, H.
    Keogh, A.
    Boffini, M.
    Bara, C.
    Zuckermann, A.
    Lopez, P.
    Cines, M.
    Lehmkuhl, H.
    TRANSPLANTATION, 2012, 94 (10) : 129 - 129
  • [23] Everolimus Immunosuppression in De Novo Heart Transplant Recipients: Clinical and Intravascular Ultrasound Study
    Choi, H.
    Hong, J.
    Kim, M.
    Lee, S.
    Kim, J.
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2019, 38 (04): : S280 - S280
  • [24] mTOR Inhibition and Hepatic Artery Thrombosis in de Novo Liver Transplant Recipients - Mitigation Strategy with Everolimus: 12 Month Results from Study H2304
    Jonas, S.
    Chapman, W.
    McCormack, L.
    Burroughs, Gordon S.
    Alsina, A.
    Junge, G.
    Witte, S.
    Hexham, J. M.
    Fischer, L.
    TRANSPLANTATION, 2012, 94 (10) : 132 - 132
  • [25] Lower Incidence of Viral Infections with Everolimus Versus MMF in De Novo Heart Transplant Recipients: 12 Month Analysis of a Randomized Multicenter Study
    Ross, H.
    Kfoury, A. G.
    Van Bakel, A.
    Ewald, G.
    Burton, J.
    Andreassen, A.
    Segovia, J.
    Lopez, P.
    Cines, M.
    Dong, G.
    Potena, L.
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2011, 30 (04): : S63 - S64
  • [26] Pharmacokinetics of Everolimus When Combined with Tacrolimus: Results from the ASSET Study in De Novo Renal Transplant Recipients
    Pascual, J.
    Rostaing, L.
    Machein, U.
    Kovarik, J. M.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2012, 12 : 299 - 299
  • [27] Exposure to CsA, and not to everolimus, is associated with impaired renal function in de novo heart transplant recipients.
    Varnous, Shaida
    Livi, Ugolino
    Poncelet, Alain
    Delgado, Juan
    Vermes, Emmanuelle
    Li, Yulan
    Arizon, Jose
    AMERICAN JOURNAL OF TRANSPLANTATION, 2008, 8 : 346 - 346
  • [28] Hospitalization days due to Major cardiac events (MACE) in De Novo heart transplant recipients:: Data from a 12-month, multicenter, randomized trial of everolimus versus MMF
    Lebmkuhl, H.
    Arizon, J.
    Almentar, L.
    Magelli, C.
    Gerosa, G.
    Varnous, S.
    Musumeci, F.
    Mattei, M. -F.
    Vanbaecke, J.
    Mange, K.
    Machnicki, G.
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2008, 27 (02): : S228 - S228
  • [29] More adverse events leading to drug dose adjustment/interruption in the presence of MMF- vs everolimus-based inummosuppression in De Novo heart transplant patients
    Vermes, E.
    Almenar, L.
    Vigano, M.
    MacCherini, M.
    Poncelet, A.
    Mattei, M. -F.
    Dengler, T.
    Delgado, J.
    Vanhaecke, J.
    Hexbam, M.
    Mange, K.
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2008, 27 (02): : S227 - S228
  • [30] Optimizing the Safety Profile of Everolimus by Delayed Initiation in De Novo Heart Transplant Recipients: Results of the Prospective Randomized Study EVERHEART
    Potena, Luciano
    Pellegrini, Carlo
    Grigioni, Francesco
    Amarelli, Cristiano
    Livi, Ugolino
    Maccherini, Massimo
    Masciocco, Gabriella
    Faggian, Giuseppe
    della Monica, Paola Lilla
    Gerosa, Gino
    Marraudino, Nicola
    Gorda, Marco
    Boffini, Massimo
    TRANSPLANTATION, 2018, 102 (03) : 493 - 501