Hypoxia-Induced Changes in microRNA Levels Contribute to Drug Resistance in a 3D Model of Malignant Pleural Mesothelioma

被引：0
|
作者：
Cheng, Yuen Yee [1 ]
Wang, Yiwei [2 ]
Sarun, Kadir [1 ]
Kirschner, Michaela [3 ]
Pellegrini, Laura [4 ]
Yang, Haining [4 ]
Carbone, David [4 ]
Mutti, Luciano [5 ]
Van Zandwijk, Nico [1 ]
Lin, Ruby [1 ]
Reid, Glen [1 ]
机构：
[1] Asbestos Dis Res Inst, Sydney, NSW, Australia
[2] Anzac Res Inst, Burns Res, Sydney, NSW, Australia
[3] Univ Hosp Zurich, Div Thorac Surg, Zurich, Switzerland
[4] Univ Hawaii, Thorac Oncol Program, Honolulu, HI USA
[5] Univ Salford, Sch Environm & Life Sci, Salford, Lancs, England
来源：
JOURNAL OF THORACIC ONCOLOGY | 2017年 / 12卷 / 01期
关键词：
Mesothelioma; microRNA; drug resistance; Hypoxia;
D O I：
10.1016/j.jtho.2016.11.1907
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P3.03-008
引用
收藏
页码：S1348 / S1348
页数：1
相关论文
共 50 条
  • [31] Biomimetic 3D Environment Based on Microgels as a Model for the Generation of Drug Resistance in Multiple Myeloma
    Marin-Paya, Juan Carlos
    Diaz-Benito, Blanca
    Martins, Luis Amaro
    Trujillo, Sandra Clara
    Cordon, Lourdes
    Lanceros-Mendez, Senentxu
    Gallego Ferrer, Gloria
    Sempere, Amparo
    Gomez Ribelles, Jose Luis
    MATERIALS, 2021, 14 (23)
  • [32] RECAPITULATING INSULIN RESISTANCE IN A 3D HUMAN LIVER MODEL FOR EFFICACY TESTING OF DRUG CANDIDATES
    Hoelting, Lisa
    Kostadinova, Radina
    Hutter, Simon
    Menghini, Arianna
    Zehnder, Anna
    Moritz, Wolfgang
    Stroebel, Simon
    Verdegue, Francisco
    Frey, Olivier
    HEPATOLOGY, 2022, 76 : S806 - S807
  • [33] Recapitulating insulin resistance in a 3D human liver model for efficacy testing of drug candidates
    Kostadinova, Radina
    Hoelting, Lisa
    Hutter, Simon
    Menghini, Arianna
    Zehnder, Anna
    Moritz, Wolgang
    Verdeguer, Francisco
    Frey, Olivier
    JOURNAL OF HEPATOLOGY, 2022, 77 : S703 - S703
  • [34] Developing a 3D Physical Model of HIV Protease to Explore Drug Resistance to Tipranavir and Darunavir
    Dyrma, Sherina
    Van Acker, Cyndi
    Nooh, Asha
    Palacios, Alessia
    Martinez-Vaz, Betsy
    FASEB JOURNAL, 2020, 34
  • [35] Hypoxia Induced Angiogenesis at 12 Weeks in a 3D Mouse Xenograft Model: Immunohistochemical Analysis.
    Britten, Joy L.
    Malik, Minnie
    Catherino, William H.
    REPRODUCTIVE SCIENCES, 2019, 26 : 133A - 133A
  • [36] Development of unenhanced CT-based imaging signature for BAP1 mutation status prediction in malignant pleural mesothelioma: Consideration of 2D and 3D segmentation
    Xie, Xiao-Jie
    Liu, Si-Yun
    Chen, Jian-You
    Zhao, Yi
    Jiang, Jie
    Wu, Li
    Zhang, Xing-Wen
    Wu, Yi
    Duan, Hui
    He, Bing
    Luo, Heng
    Han, Dan
    LUNG CANCER, 2021, 157 : 30 - 39
  • [37] The development of a 3D cell-culture model of drug-induced oral mucositis
    Lambros, Maria P.
    Fei, QinQin
    Moreno, Jonathan
    CANCER RESEARCH, 2019, 79 (13)
  • [38] Co-culture of 3D tumor spheroids with fibroblasts as an in vitro model for drug resistance study
    Kim, Sun-Ah
    Kuh, Hyo-Jeong
    CANCER RESEARCH, 2014, 74 (19)
  • [39] ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway
    Xiang-jun Wang
    Chang-wei Feng
    Min Li
    Molecular and Cellular Biochemistry, 2013, 380 : 57 - 66
  • [40] ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway
    Wang, Xiang-jun
    Feng, Chang-wei
    Li, Min
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2013, 380 (1-2) : 57 - 66
12345