Fe(HSO4)3 as an efficient catalyst for the preparation of 3,4-dihydropyrimidin-2(1H)-ones in solution and under solvent-free conditions

被引：44
|
作者：
Shirini, F. [1 ]
Zolfigol, M. A. [2 ]
Abri, A. -R. [1 ]
机构：
[1] Univ Guilan, Coll Sci, Dept Chem, Rasht 41335, Iran
[2] Bu Ali Sina Univ, Fac Chem, Hamaden 6517838683, Iran
来源：
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2008年 / 5卷 / 01期
关键词：
3,4-dihydropyrimidin-2(1H)-ones; solvent-free conditions; Biginelli reaction; three-component condensation; Fe(HSO4)(3);
D O I：
10.1007/BF03245821
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A one-pot three-component condensation of aromatic aldehydes, beta-ketoesters and urea or thiourea, efficiently promoted in the presence of Fe(HSO4)(3) in solution and under solvent-free conditions, produced 3,4-dihydropyrimidin-2(1H)-ones. The method offers several advantages including simple, easy and clean work-up procedure, relatively short reaction times and good to high yields of the products.
引用
收藏
页码：96 / 99
页数：4
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