Mycophenolate Sodium for Children with Frequently Relapsing or Steroid Dependent Nephrotic Syndrome

被引：3
|
作者：
Kapoor, Kanika [1 ,2 ]
Saha, Abhijeet [1 ,2 ]
Kaur, Manpreet [1 ,2 ]
Dubey, Nand Kishore [1 ,2 ]
Upadhyay, Ashish Datt [3 ]
机构：
[1] PGIMER, Dept Pediat, New Delhi, India
[2] Dr Ram Manohar Lohia Hosp, New Delhi, India
[3] AIIMS, Dept Biostat, New Delhi, India
来源：
INDIAN PEDIATRICS | 2017年 / 54卷 / 10期
关键词：
Minimal change disease; Proteinuria; Refractory; Treatment; MOFETIL; PREDNISOLONE;
D O I：
10.1007/s13312-017-1156-5
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
In this retrospective study, patients with idiopathic frequentlyrelapsing nephrotic syndrome (FRNS) (n = 27) and steroid dependent nephrotic syndrome (SDNS) (n = 13) who received enteric coated mycophenolate sodium (ECMS) for at least 6 months, were included for analysis. Primary outcome was response to ECMS, which was defined as complete if there were no relapses, partial response if there was 1 relapse and no response if there were 2 or more relapses within 6 months of initiation. The mean (SD) dose of ECMS was 985.24 (190.82) mg/m(2)/day. Thirty patients(75%) had complete response, eight (20%) had partial and two (5%) patients did not respond at 6 months. ECMS seems to be a safe and effective as steroid sparing agent in children with FRNS/SDNS.
引用
收藏
页码：885 / 886
页数：2
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