Synthesis and dehydration of exo-2-(3-R-5-isoxazolyl)-5,6,6-trimethylbicyclo[2.2.1]heptan-endo-2-ols

被引：0

作者：

Bondar, NF ^{[1
]}

Koval'skaya, SS ^{[1
]}

Skupskaya, RV ^{[1
]}

Dikusar, EA ^{[1
]}

Kozlov, NG ^{[1
]}

Lakhvich, FA ^{[1
]}

机构：

[1] Byelarussian Acad Sci, Inst Phys Organ Chem, Minsk 220078, BELARUS

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2000年 / 36卷 / 11期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of nitrile oxides with 2-exo-ethynyl-5,6,6-trimethyihicyclo[2.2.1]heptan-2-endo-ol resulted in 2-exo-(3-R-5-isoxazolyl)-5,6,6-trimethylbicyclo[2.2.1]heptan-2-endo-ols that on treatment with methanesulfonyl chloride in pyridine underwent dehydration to afford a mixture of 2-exo-(3-R-5-isoxazolyl)-5,5,6-trimethyl bicyclo[2.2.1]hept-2-ene and 2-(3-R-5-Isoxazolyl)-4,7,7-trimethylbicyclo[2.2.1]hept-2-ene in 3:1 ratio.

引用

页码：1607 / 1611

页数：5

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