Synthesis and dehydration of exo-2-(3-R-5-isoxazolyl)-5,6,6-trimethylbicyclo[2.2.1]heptan-endo-2-ols

被引：0
|
作者：
Bondar, NF [1 ]
Koval'skaya, SS [1 ]
Skupskaya, RV [1 ]
Dikusar, EA [1 ]
Kozlov, NG [1 ]
Lakhvich, FA [1 ]
机构：
[1] Byelarussian Acad Sci, Inst Phys Organ Chem, Minsk 220078, BELARUS
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2000年 / 36卷 / 11期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction of nitrile oxides with 2-exo-ethynyl-5,6,6-trimethyihicyclo[2.2.1]heptan-2-endo-ol resulted in 2-exo-(3-R-5-isoxazolyl)-5,6,6-trimethylbicyclo[2.2.1]heptan-2-endo-ols that on treatment with methanesulfonyl chloride in pyridine underwent dehydration to afford a mixture of 2-exo-(3-R-5-isoxazolyl)-5,5,6-trimethyl bicyclo[2.2.1]hept-2-ene and 2-(3-R-5-Isoxazolyl)-4,7,7-trimethylbicyclo[2.2.1]hept-2-ene in 3:1 ratio.
引用
收藏
页码：1607 / 1611
页数：5
相关论文
共 50 条
  • [1] Synthesis and Dehydration of endo-2-(3-R-Isoxazol-5-yl)-1,7,7-trimethylbicyclo[2.2.1]heptan-exo-2-ols
    N. F. Bondar'
    S. S. Koval'skaya
    R. V. Skupskaya
    F. S. Pashkovskii
    E. A. Dikusar
    N. G. Kozlov
    F. A. Lakhvich
    Russian Journal of Organic Chemistry, 2001, 37 : 23 - 28
  • [2] Synthesis and dehydration of endo-2-(3-R-isoxazol-5-yl)-1,7,7-trimethylbicyclo[2.2.1]heptan-exo-2-ols
    Bondar, NF
    Koval'skaya, SS
    Skupskaya, RV
    Pashkovskii, FS
    Dikusar, EA
    Kozlov, NG
    Lakhvich, FA
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2001, 37 (01) : 23 - 28
  • [3] Synthesis of 5,5,6-trimethylbicyclo[2.2.1]heptan-2-one
    Kozlov, NG
    Popova, LA
    ZHURNAL ORGANICHESKOI KHIMII, 1997, 33 (03): : 371 - 377
  • [4] Synthesis and reactivity of 3-(5′,5′,6′-trimethylbicyclo[2.2.1]-hept-2′-ylidene)-5,5,6-trimethylbicyclo[2.2.1]heptan-2-one
    Kozlov, NG
    Katash, LS
    ZHURNAL ORGANICHESKOI KHIMII, 1998, 34 (01): : 52 - 55
  • [5] Synthesis and Ritter reaction of 3-exo-hydroxymethyl-5,5,6-trimethylbicyclo[2.2.1]heptan-2-one
    Koval'skaya, SS
    Kozlov, NG
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2003, 73 (09) : 1421 - 1425
  • [6] Synthesis and Ritter reaction of endo-2-ethynyl-1,7,7-trimethyl- and exo-2-ethynyl-5,5,6-trimethylbicyclo[2.2.1]heptan-2-ols
    Koval'skaya, SS
    Kozlov, NG
    Dikusar, EA
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2000, 36 (03) : 379 - 385
  • [7] Synthesis and Ritter Reaction of 3-exo-Hydroxymethyl-5,5,6-trimethylbicyclo[2.2.1]heptan-2-one
    S. S. Koval'skaya
    N. G. Kozlov
    Russian Journal of General Chemistry, 2003, 73 : 1421 - 1425
  • [8] RITTER REACTION OF 5,5,6-TRIMETHYLBICYCLO[2.2.1]HEPTAN-2-EXO-OL WITH ACETONITRILE AND BENZONITRILE
    KOZLOV, NG
    NESTEROV, GV
    MAKHNACH, SA
    ZHURNAL OBSHCHEI KHIMII, 1985, 55 (09): : 2097 - 2100
  • [9] SYNTHESIS OF DIPEROXYKETALS BASED ON 5,5,6-TRIMETHYLBICYCLO [2.2.1] HEPTAN-2-ONE
    YUVCHENKO, AP
    BERESNEVICH, LB
    ZHUKOVSKAYA, NA
    KOZLOV, NG
    MOISEICHUK, KL
    OLDEKOP, YA
    ZHURNAL ORGANICHESKOI KHIMII, 1988, 24 (09): : 1889 - 1893
  • [10] Synthesis of 3-(2-hydroxy-5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)-5,5,6-trimethylbicyclo[2.2.1]heptan-2-one and its derivatives
    Kozlov, NG
    Yakubovich, LS
    ZHURNAL ORGANICHESKOI KHIMII, 1999, 35 (06): : 866 - 868
12345