Hepatic Adenomas Caused by Somatic HNF1A Mutations in Children With Biallelic Mismatch Repair Gene Mutations

被引：17
|
作者：
Holter, Spring [1 ]
Pollett, Aaron [1 ]
Zogopoulos, George [1 ]
Kim, Hyeja [1 ]
Schwenter, Frank [1 ]
Asai, Kengo [1 ]
Gallinger, Steven [1 ]
Clendenning, Mark [2 ]
Steinbach, Gideon [3 ]
Jacobson, Angela [3 ]
Boycott, Kym M. [4 ]
机构：
[1] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Zane Cohen Ctr Digest Dis, Toronto, ON M5G 1X5, Canada
[2] Queensland Inst Med Res, Familial Canc Lab, Brisbane, Qld 4006, Australia
[3] Seattle Canc Care Alliance Canc Prevent Program, Seattle, WA USA
[4] Childrens Hosp Eastern Ontario, Dept Genet, Ottawa, ON K1H 8L1, Canada
来源：
GASTROENTEROLOGY | 2011年 / 140卷 / 02期
基金：
加拿大健康研究院;
关键词：
CANCERS;
D O I：
10.1053/j.gastro.2010.11.051
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：735 / 736
页数：2
相关论文
共 50 条
  • [21] Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas
    Clendenning, Mark
    Huang, Alvin
    Jayasekara, Harindra
    Lorans, Marie
    Preston, Susan
    O'Callaghan, Neil
    Pope, Bernard J.
    Macrae, Finlay A.
    Winship, Ingrid M.
    Milne, Roger L.
    Giles, Graham G.
    English, Dallas R.
    Hopper, John L.
    Win, Aung K.
    Jenkins, Mark A.
    Southey, Melissa C.
    Rosty, Christophe
    Buchanan, Daniel D.
    FAMILIAL CANCER, 2018, 17 (01) : 91 - 100
  • [22] Mismatch Repair Deficiency and Somatic Mutations in Human Sinonasal Tumors
    Hieggelke, Lena
    Heydt, Carina
    Castiglione, Roberta
    Rehker, Jan
    Merkelbach-Bruse, Sabine
    Riobello, Cristina
    Llorente, Jose Luis
    Hermsen, Mario A.
    Buettner, Reinhard
    CANCERS, 2021, 13 (23)
  • [23] Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A
    Cardenas-Diaz, Fabian L.
    Osorio-Quintero, Catherine
    Diaz-Miranda, Maria A.
    Kishore, Siddharth
    Leavens, Karla
    Jobaliya, Chintan
    Stanescu, Diana
    Ortiz-Gonzalez, Xilma
    Yoon, Christine
    Chen, Christopher S.
    Haliyur, Rachana
    Brissova, Marcela
    Powers, Alvin C.
    French, Deborah L.
    Gadue, Paul
    CELL STEM CELL, 2019, 25 (02) : 273 - +
  • [24] Biallelic inactivation by somatic mutations of the MEN1 gene in sporadic parathyroid tumors
    Tanaka, C
    Uchino, S
    Noguchi, S
    Nishioka, T
    Yamasaki, H
    Hashimoto, K
    Yoshimoto, K
    CANCER LETTERS, 2002, 175 (02) : 175 - 179
  • [25] Biallelic somatic inactivation of the mismatch repair gene MLH1 in a primary skin melanoma
    Castiglia, D
    Pagani, E
    Alvino, E
    Vernole, P
    Marra, G
    Cannavò, E
    Jiricny, J
    Zambruno, G
    D'Atri, S
    GENES CHROMOSOMES & CANCER, 2003, 37 (02): : 165 - 175
  • [26] The spectrum of HNF1A gene mutations in Greek patients with MODY3: relative frequency and identification of seven novel germline mutations
    Tatsi, Christina
    Kanaka-Gantenbein, Christina
    Vazeou-Gerassimidi, Adriani
    Chrysis, Dionysios
    Delis, Dimitrios
    Tentolourisd, Nikolaos
    Dacou-Voutetakis, Catherine
    Chrousos, George P.
    Sertedaki, Amalia
    PEDIATRIC DIABETES, 2013, 14 (07) : 526 - 534
  • [27] Increased all-cause and cardiovascular mortality in monogenic diabetes as a result of mutations in the HNF1A gene
    Steele, A. M.
    Shields, B. M.
    Shepherd, M.
    Ellard, S.
    Hattersley, A. T.
    Pearson, E. R.
    DIABETIC MEDICINE, 2010, 27 (02) : 157 - 161
  • [28] Hepatic Adenomas in Patients 60 and Older Are Enriched for HNF1A Inactivation and Malignant Transformation
    Yasir, Saba
    Chen, Zongming E.
    Jain, Dhanpat
    Kakar, Sanjay
    Wu, Tsung-Teh
    Yeh, Matthew M.
    Torbenson, Michael S.
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2022, 46 (06) : 786 - 792
  • [29] Somatic mutations of the ATP1A1 gene and aldosterone-producing adenomas
    Gomez-Sanchez, Celso E.
    Kuppusamy, Maniselvan
    Gomez-Sanchez, Elise P.
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2015, 408 (0C) : 213 - 219
  • [30] Cafe-au-lait macules and pediatric malignancy caused by biallelic mutations in the DNA mismatch repair (MMR) gene PMS2
    Jackson, Carl-Christian
    Holter, Spring
    Pollett, Aaron
    Clendenning, Mark
    Chou, Shirley
    Senter, Leigha
    Ramphal, Raveena
    Gallinger, Steven
    Boycott, Kym
    PEDIATRIC BLOOD & CANCER, 2008, 50 (06) : 1268 - 1270
12345