Response of the middle cerebral artery to serotonin

被引：0
|
作者：
Mirzoyan, RS
Semkina, GA
Matsievskii, DD
机构：
[1] Russian Acad Med Sci, Inst Pharmacol, Lab Pharmacol Cerebrovasc Disorders, Moscow 109801, Russia
[2] Russian Acad Med Sci, Inst Gen Pathol & Pathophysiol, Lab Bioengn, Moscow, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1997年 / 124卷 / 10期
关键词：
serotonin; ultrasonography; cerebral blood flow; middle cerebral artery;
D O I：
10.1007/BF02446841
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The effect of serotonin on blood flow in the middle cerebral and common carotid arteries was studied with the help of Doppler ultrasonography on Wistar rats under general anesthesia. Serotonin induced a constrictor-dilator reaction ill the middle cerebral artery: in 50% of experiments a marked initial blood flow drop was followed by a moderate increase, and then again by a profound and long decrease of the blood flow. At the same time the blood now augmented in the common carotid artery. The data shaw selective and mostly vasoconstrictor effect of serotonin of the middle cerebral artery system.
引用
收藏
页码：988 / 991
页数：4
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