Visible-Light-Mediated α-Oxygenation of 3-(N,N-Dimethylaminomethyl)-Indoles to Aldehydes

被引：10
|
作者：
Stanek, Filip [1 ]
Pawlowski, Robert [1 ]
Mlynarski, Jacek [1 ]
Stodulski, Maciej [1 ]
机构：
[1] Polish Acad Sci, Inst Organ Chem, Kasprzaka 44-52, PL-01224 Warsaw, Poland
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 2018卷 / 47期
关键词：
Photocatalysis; Bronsted acids; Photoredox; Oxygenation; Indole; SINGLET-OXYGEN; PHOTOREDOX CATALYSIS; AEROBIC OXIDATION; CARBONYL-COMPOUNDS; ELECTRON-TRANSFER; ALIPHATIC-AMINES; NATURAL-PRODUCTS; TERTIARY-AMINES; EOSIN Y; GENERATION;
D O I：
10.1002/ejoc.201801335
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The visible-light-mediated oxygenation of 3-N,N-(dimethylaminomethyl)-indoles bearing various substituents afforded a series of 3-carbaindole derivatives. Herein we describe the reaction scope, a plausible mechanism and a practical application of this transformation in the formal synthesis of (-)-vincorine is described as well.
引用
收藏
页码：6624 / 6628
页数：5
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