Allergic skin diseases

被引：100

作者：

Fonacier, Luz S. ^{[2
]}

Dreskin, Stephen C. ^{[3
]}

Leung, Donald Y. M. ^{[1
]}

机构：

[1] Natl Jewish Hlth, Denver, CO 80206 USA

[2] Winthrop Univ Hosp, Mineola, NY 11501 USA

[3] Univ Colorado Denver, Aurora, CO USA

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2010年 / 125卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Allergic contact dermatitis; autoimmune blistering disease; atopic dermatitis; eczema; immune-mediated skin disorders; irritant contact dermatitis; psoriasis; urticaria; PLASMACYTOID DENDRITIC CELLS; ATOPIC-DERMATITIS; CONTACT-DERMATITIS; CHRONIC URTICARIA; EYELID DERMATITIS; THERAPEUTIC ALTERNATIVES; ANTIMICROBIAL PEPTIDES; STAPHYLOCOCCUS-AUREUS; FILAGGRIN MUTATIONS; FECAL MICROBIOTA;

D O I：

10.1016/j.jaci.2009.05.039

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The skin is one of the largest immunologic organs and is affected by both external and internal factors, as well as innate and adaptive immune responses. Many skin disorders, such as atopic dermatitis, contact dermatitis, urticaria, angioedema, psoriasis, and autoimmune blistering disorders, are immune mediated. Most of these diseases are chronic, inflammatory, and proliferative, in which both genetic and environmental factors play important roles. These immunologic mechanisms might have implications for potential targets of future therapeutic interventions. (J Allergy Clin Immunol 2010;125:S138-49.)

引用

页码：S138 / S149

页数：12

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