The cytotoxicity of Saponins correlates with their cellular internalization

被引：16
|
作者：
Wang, Yibing
Zhang, Yichun
Yu, Biao
机构：
[1] State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
来源：
CHEMMEDCHEM | 2007年 / 2卷 / 03期
关键词：
Cellular internalization; Cytotoxicity; Fluorescent probes; Lysosomes; Spirostan saponin;
D O I：
10.1002/cmdc.200600235
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Saponins however, do not anchor themselves to are a broad class of plant-derived compounds the cell membrane, but are instead compounds that are commonly used as a internalized. They localize specifically to tool to disrupt cell membranes. Some acidic organelles such as lysosomes, and saponins such as that shown above,
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收藏
页码：288 / +
页数：5
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