Model for inhibition of HCV NS5b polymerase by nucleoside analogs

被引：0
|
作者：
Perry, Jason K. [1 ]
机构：
[1] Gilead Sci Inc, Struct Chem, Foster City, CA 94404 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 242卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
202-COMP
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Classification of HCV NS5B Polymerase Inhibitors Using Support Vector Machine
    Wang, Maolin
    Wang, Kai
    Yan, Aixia
    Yu, Changyuan
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2012, 13 (04) : 4033 - 4047
  • [42] Discovery of new scaffolds for rational design of HCV NS5B polymerase inhibitors
    Golub, Andriy G.
    Gurukumar, K. R.
    Basu, Amartya
    Bdzhola, Volodymyr G.
    Bilokin, Yaroslav
    Yarmoluk, Sergiy M.
    Lee, Jin-Ching
    Talele, Tanaji T.
    Nichols, Daniel B.
    Kaushik-Basu, Neerja
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 58 : 258 - 264
  • [43] In Silico Studies of Crystal Structure of HCV NS5B Polymerase and Inhibitor Complex
    Tiwari, Gargi
    Pandey, Vishnudatt
    Tiwari, Rakesh Kumar
    Ojha, Rajendra Prasad
    MATERIALS TODAY-PROCEEDINGS, 2018, 5 (07) : 15431 - 15438
  • [44] 2-Heteroarylimino-5-arylidene-4-thiazolidinones as a new class of non-nucleoside inhibitors of HCV NS5B polymerase
    Kucukguzel, Ilkay
    Satilmis, Gokhan
    Gurukumar, K. R.
    Basu, Amartya
    Tatar, Esra
    Nichols, Daniel B.
    Talele, Tanaji T.
    Kaushik-Basu, Neerja
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 69 : 931 - 941
  • [45] PRECLINICAL PHARMACOKINETIC AND ADME CHARACTERIZATION OF VCH-222, A NOVEL NON-NUCLEOSIDE HCV NS5B POLYMERASE INHIBITOR
    Chauret, N.
    Chagnon-Labelle, C.
    Diallo, M.
    Laquerre, J.
    Laterreur, J.
    May, S.
    Ste-Marie, L.
    JOURNAL OF HEPATOLOGY, 2009, 50 : S341 - S342
  • [46] Non-nucleoside inhibitors binding to hepatitis C virus NS5B polymerase reveal a novel mechanism of inhibition
    Biswal, Bichitra K.
    Wang, Meitian
    Cherney, Maia M.
    Chan, Laval
    Yannopoulos, Constantin G.
    Bilimoria, Darius
    Bedard, Jean
    James, Michael N. G.
    JOURNAL OF MOLECULAR BIOLOGY, 2006, 361 (01) : 33 - 45
  • [47] Synthesis of New 4, 5-Dihydrofuranoindoles and Their Evaluation as HCV NS5B Polymerase Inhibitors
    Velazquez, Francisco
    Venkatraman, Srikanth
    Lesburg, Charles A.
    Duca, Jose
    Rosenblum, Stuart B.
    Kozlowski, Joseph A.
    Njoroge, F. George
    ORGANIC LETTERS, 2012, 14 (02) : 556 - 559
  • [48] Discovery and initial optimization of alkoxyanthranilic acid derivatives as inhibitors of HCV NS5B polymerase
    Parcella, Kyle
    Nickel, Andrew
    Beno, Brett R.
    Sheriff, Steven
    Wan, Changhong
    Wang, Ying-Kai
    Roberts, Susan B.
    Meanwell, Nicholas A.
    Kadow, John F.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (02) : 295 - 298
  • [49] The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase
    Eastman, Kyle J.
    Parcella, Kyle
    Yeung, Kap-Sun
    Grant-Young, Katharine A.
    Zhu, Juliang
    Wang, Tao
    Zhang, Zhongxing
    Yin, Zhiwei
    Beno, Brett R.
    Sheriff, Steven
    Kish, Kevin
    Tredup, Jeffrey
    Jardel, Adam G.
    Halan, Vivek
    Ghosh, Kaushik
    Parker, Dawn
    Mosure, Kathy
    Fang, Hua
    Wang, Ying-Kai
    Lemm, Julie
    Zhuo, Xiaoliang
    Hanumegowda, Umesh
    Rigat, Karen
    Donoso, Maria
    Tuttle, Maria
    Zvyaga, Tatyana
    Haarhoff, Zuzana
    Meanwell, Nicholas A.
    Soars, Matthew G.
    Roberts, Susan B.
    Kadow, John F.
    MEDCHEMCOMM, 2017, 8 (04) : 796 - 806
  • [50] Discovery of Terpenes as Novel HCV NS5B Polymerase Inhibitors via Molecular Docking
    Karpinski, Tomasz. M. M.
    Ozarowski, Marcin
    Silva, Pedro. J. J.
    Stasiewicz, Mark
    Alam, Rahat
    Samad, Abdus
    PATHOGENS, 2023, 12 (06):
12345