Constipation in childhood

被引:104
|
作者
Mugie, Suzanne M. [1 ]
Di Lorenzo, Carlo [2 ]
Benninga, Marc A. [1 ]
机构
[1] Univ Amsterdam, Acad Med Ctr, Emma Childrens Hosp, NL-1105 AZ Amsterdam, Netherlands
[2] Nationwide Childrens Hosp, Dept Pediat Gastroenterol Hepatol & Nutr, Columbus, OH 43205 USA
关键词
SLOW-TRANSIT CONSTIPATION; DIRECT MEDICAL COSTS; DIETARY FIBER INTAKE; DOUBLE-BLIND; COLONIC TRANSIT; INTRACTABLE CONSTIPATION; PLUS ELECTROLYTES; FECAL IMPACTION; FUNCTIONAL CONSTIPATION; INTERSTITIAL-CELLS;
D O I
10.1038/nrgastro.2011.130
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Constipation in children is an often long-lasting pediatric functional gastrointestinal disorder with a worldwide prevalence varying between 0.7% and 29.6%, and estimated health-care costs of US$3.9 billion per year in the USA alone. The pathophysiology of childhood constipation is multifactorial and remains incompletely understood; however, withholding of stools, starting after an experience of a hard, painful, or frightening bowel movement is the most common cause found in children. A thorough medical history and physical examination, including a rectal examination in combination with a bowel diary, is sufficient in the majority of cases to diagnose constipation. The current standard treatment consists of education, toilet training, disimpaction, maintenance therapy and long-term follow-up. In the past decade, well-designed treatment trials in the pediatric population have emerged and long-term outcome studies have been completed. This Review summarizes the current knowledge of the clinical aspects of childhood constipation, including pathogenesis, diagnosis and treatment, with particular emphasis on the latest available data.
引用
收藏
页码:502 / 511
页数:10
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