DIABETES Dapagliflozin-redefining treatment of T2DM?

被引：1
|
作者：
Chao, Edward C. [1 ,2 ]
机构：
[1] Univ Calif San Diego, Div Endocrinol & Metab, San Diego, CA 92161 USA
[2] VA San Diego, San Diego, CA 92161 USA
来源：
NATURE REVIEWS ENDOCRINOLOGY | 2011年 / 7卷 / 12期
关键词：
INADEQUATE GLYCEMIC CONTROL; PLACEBO-CONTROLLED TRIAL; DOUBLE-BLIND; METFORMIN; THERAPY;
D O I：
10.1038/nrendo.2011.177
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Glycemic control for many patients with type 2 diabetes mellitus (T2DM) is elusive, and the adverse effects of treatment, including hypoglycemia and weight gain, are partially culpable. Until recently, glycosuria has been regarded only as a consequence of T2DM, but dapagliflozin employs glycosuria as a mechanism of treatment. Will this paradigm shift gain acceptance?
引用
收藏
页码：696 / 697
页数：3
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