A Case of SGLT2 Inhibitor-Induced Euglycemic Diabetic Ketoacidosis

被引：0
|
作者：
Rao, Shiavax J. [1 ]
Kumar, Kaushik [1 ]
Saleh, Nahar [1 ]
机构：
[1] MedStar Union Mem Hosp, Internal Med, Baltimore, MD 21218 USA
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2022年 / 14卷 / 10期
关键词：
high anion gap metabolic acidosis; sglt-2; inhibitor; euglycemic dka; diabetic keto acidosis; sodium-glucose cotransporter-2 inhibitors;
D O I：
10.7759/cureus.30106
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
While rare, serious adverse effects including euglycemic diabetic ketoacidosis (EDKA) have been associated with sodium-glucose cotransporter-2 inhibitor (SGLT2i) use. We present an interesting case of SGLT2i-induced EDKA occurring two years after initiation of therapy. Most patients with EDKA recover with prompt recognition and treatment. Patient education about identifying early signs remains a cornerstone of early identification and response to SGLT2i-induced EDKA.
引用
收藏
页数：4
相关论文
共 50 条
  • [31] Sodium-Glucose Co-Transporter-2 (SGLT2) Inhibitor-Related Euglycemic Diabetic Ketoacidosis: A Case Series
    Meier, Mackenzi
    Ansong, Benedicta
    Awobusuyi, Dolapo
    Lee-Oyagha, Raven
    Lopez, Sarah
    JOURNAL OF PHARMACY PRACTICE, 2025, 38 (01) : 193 - 197
  • [32] Pathogenesis of euglycemic ketoacidosis associated with SGLT2 inhibitors
    Sitina, M.
    Sramek, V
    ANESTEZIOLOGIE A INTENZIVNI MEDICINA, 2024, 35 (02): : 98 - 103
  • [33] Understanding the disease: euglycemic ketoacidosis with SGLT2 inhibitors
    Malherbe, Jolan
    du Cheyron, Damien
    Valette, Xavier
    INTENSIVE CARE MEDICINE, 2025,
  • [34] Risk of Diabetic Ketoacidosis after Initiation of an SGLT2 Inhibitor
    Fralick, Michael
    Schneeweiss, Sebastian
    Patorno, Elisabetta
    NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (23): : 2300 - 2302
  • [35] SGLT2 inhibitor-related risk of diabetic ketoacidosis
    Reactions Weekly, 2016, 1590 (1) : 7 - 7
  • [36] Preoperative SGLT2 Inhibitor Use and Postoperative Diabetic Ketoacidosis
    Dixit, Anjali A.
    Bateman, Brian T.
    Hawn, Mary T.
    Odden, Michelle C.
    Sun, Eric C.
    JAMA SURGERY, 2025,
  • [37] Diabetic ketoacidosis with SGLT2 inhibitor use - a patient series
    Lejlic, Selma
    Holmaas, Gunhild
    Lovas, Kristian
    Ueland, Grethe Astrom
    TIDSSKRIFT FOR DEN NORSKE LAEGEFORENING, 2023, 143 (03) : 235 - 238
  • [38] Life-threatening coronary vasospasm in patients with type 2 diabetes with SGLT2 inhibitor-induced euglycemic ketoacidosis: a report of two consecutive cases
    Junko Kawahara
    Bunji Kaku
    Kunimasa Yagi
    Naotaka Kitagawa
    Maki Yokoyama
    Yusuke Wakabayashi
    Satoko Senda
    Hiroyuki Takata
    Yoshio Hiraiwa
    Diabetology International, 2024, 15 : 135 - 140
  • [39] Life-threatening coronary vasospasm in patients with type 2 diabetes with SGLT2 inhibitor-induced euglycemic ketoacidosis: a report of two consecutive cases
    Kawahara, Junko
    Kaku, Bunji
    Yagi, Kunimasa
    Kitagawa, Naotaka
    Yokoyama, Maki
    Wakabayashi, Yusuke
    Senda, Satoko
    Takata, Hiroyuki
    Hiraiwa, Yoshio
    DIABETOLOGY INTERNATIONAL, 2024, 15 (01) : 135 - 140
  • [40] Euglycemic Diabetic Ketoacidosis: A Predictable, Detectable, and Preventable Safety Concern With SGLT2 Inhibitors
    Rosenstock, Julio
    Ferrannini, Ele
    DIABETES CARE, 2015, 38 (09) : 1638 - 1642
12345