Antibody-free detection of protein phosphorylation using intrinsic peroxidase-like activity of platinum/carbon dot hybrid nanoparticles

被引：21

作者：

Wang, Yuzhen ^{[1
,2
,3
]}

Qi, Wenjin ^{[4
]}

Song, Yujun ^{[1
]}

机构：

[1] Nanjing Univ, Coll Engn & Appl Sci, Dept Biomed Engn, Nanjing 210093, Jiangsu, Peoples R China

[2] Houston Methodist Hosp, Res Inst, Dept Nanomed, Houston, TX 77030 USA

[3] Cornell Univ, Weill Med Coll, New York, NY 10065 USA

[4] Kunming Med Univ, Affiliated Hosp 1, Dept Obstet & Gynecol, Kunming 660032, Yunnan, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 51期

基金：

中国国家自然科学基金;

关键词：

MASS-SPECTROMETRY; KINASE; RECEPTOR; PHOSPHOPROTEOME; INHIBITION; RADIATION; CANCER; CELLS;

D O I：

10.1039/c6cc02771g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Platinum and carbon dot hybrid nanomaterials are prepared for visualized detection of phosphoproteins without the need for antibodies or enzymes. This new strategy can be used for colorimetric detection of phosphoproteins induced by protein kinase as well as protein phosphorylation sites on cell membranes.

引用

页码：7994 / 7997

页数：4

共 50 条

[41] A colorimetric biosensor based on peroxidase-like activity of CuO nanoparticles for simultaneous detection of microRNAs
Mahdie, Mohadese
Rahaie, Mahdi
Shateri, Fateme
CHEMICAL PAPERS, 2022, 76 (12) : 7305 - 7312
[42] Peroxidase-like activity of chitosan stabilized silver nanoparticles for visual and colorimetric detection of glucose
Jiang, Huan
Chen, Zhaohui
Cao, Haiyan
Huang, Yuming
ANALYST, 2012, 137 (23) : 5560 - 5564
[43] Protein-directed in situ synthesis of platinum nanoparticles with superior peroxidase-like activity, and their use for photometric determination of hydrogen peroxide
Lijian Chen
Nan Wang
Xindong Wang
Shiyun Ai
Microchimica Acta, 2013, 180 : 1517 - 1522
[44] A colorimetric biosensor based on peroxidase-like activity of CuO nanoparticles for simultaneous detection of microRNAs
Mohadese Mahdie
Mahdi Rahaie
Fateme Shateri
Chemical Papers, 2022, 76 : 7305 - 7312
[45] Platinum nanoparticles confined in metal–organic frameworks as excellent peroxidase-like nanozymes for detection of uric acid
Mingyuan Xia
Shushu Chu
Shuna Wang
Xuyang Dong
Chuanxia Chen
Yuanyuan Jiang
Zhe Li
Yizhong Lu
Analytical and Bioanalytical Chemistry, 2023, 415 : 649 - 658
[46] Nitrogen and copper-doped carbon quantum dots with intrinsic peroxidase-like activity for double-signal detection of phenol
Du, Jinyan
Qi, Shuangqing
Fan, Tingting
Yang, Ying
Wang, Chaofeng
Shu, Qin
Zhuo, Shujuan
Zhu, Changqing
ANALYST, 2021, 146 (13) : 4280 - 4289
[47] Colorimetric glutathione assay based on the peroxidase-like activity of a nanocomposite consisting of platinum nanoparticles and graphene oxide
Hui-Huang Xu
Hao-Hua Deng
Xiao-Qing Lin
Yan-Yu Wu
Xiu-Ling Lin
Hua-Ping Peng
Ai-Lin Liu
Xing-Hua Xia
Wei Chen
Microchimica Acta, 2017, 184 : 3945 - 3951
[48] Metal-free colorimetric detection of pyrophosphate ions by the peroxidase-like activity of ATP
Wen, Jiahui
Huang, Na
Wei, Zixuan
Yi, Danyang
Long, Yijuan
Zheng, Huzhi
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2022, 267
[49] Three-Dimensional Branched Crystal Carbon Nitride with Enhanced Intrinsic Peroxidase-Like Activity: A Hypersensitive Platform for Colorimetric Detection
Fan, Yaofang
Zhang, Weican
Liu, Yanming
Zeng, Zhenxing
Quan, Xie
Zhao, Huimin
ACS APPLIED MATERIALS & INTERFACES, 2019, 11 (19) : 17467 - 17474
[50] A colorimetric sensor for detecting thiourea based on inhibiting peroxidase-like activity of gold-platinum nanoparticles
Zhao, Yuqi
Fu, Qingjie
Cui, Xiaoqian
Chi, Hui
Lu, Yongzhuang
Liu, Xiaoli
Yu, Miao
Fei, Qiang
Feng, Guodong
Shan, Hongyan
Huan, Yanfu
ANALYTICAL METHODS, 2021, 13 (08) : 1069 - 1074

← 1 2 3 4 5 →