Complete spontaneous bowel movement frequency as primary outcome measure in patients with chronic constipation treated with linaclotide

被引:2
|
作者
Johnston, Jeffrey M. [1 ]
Mac Dougall, James [1 ]
Lavins, Bernard J. [1 ]
Kurtz, Caroline B. [1 ]
机构
[1] Microbia Inc, Cambridge, MA USA
来源
关键词
D O I
10.14309/00000434-200709002-01078
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
1078
引用
收藏
页码:S513 / S513
页数:1
相关论文
共 50 条
  • [31] Naloxegol Accelerates Time to First Spontaneous Bowel Movement (SBM) and Complete SBM (CSBM) With Predictable Efficacy in Patients With Extreme Opioid-Induced Constipation (OIC): A Pooled Analysis of Two Phase 3 Trials
    Chey, William D.
    Brenner, Darren M.
    Adler, Jeremy
    Mallick-Searle, Theresa
    Rockett, Carol
    Bortey, Enoch
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2021, 116 : S221 - S221
  • [32] Td-1211 Phase 2B Study Demonstrates Increased Bowel Movement Frequency and Constipation-Related Symptom Improvement in Patients With Opioid Induced Constipation (OIC)
    Vickery, Ross G.
    Li, Yu-Ping
    Schwertschlag, Ullrich
    Singla, Neil K.
    Webster, Lynn
    Canafax, Daniel M.
    GASTROENTEROLOGY, 2013, 144 (05) : S159 - S159
  • [33] PAMORAs result in clinically significant improvement in spontaneous and complete spontaneous bowel movements with low risk of side effects in patients with opioid induced constipation: Systematic review and meta-analysis
    Vijayvargiya, Priya
    Camilleri, Michael
    Vijayvargiya, Pooja
    Erwin, Patricia
    Murad, M. H.
    NEUROGASTROENTEROLOGY AND MOTILITY, 2020, 32
  • [34] Efficacy and Safety of Linaclotide in Patients With Chronic Idiopathic Constipation: A Post Hoc Analysis of Phase 3 Clinical Study Data Assessing Primary and Additional Endpoints by Race and Ethnicity, and by Age
    Moshiree, Baharak
    Chang, Lin
    Boules, Mena
    Chen, Wendy
    Wu, James
    Li, Moming
    Feuerstadt, Paul
    Staller, Kyle
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2024, 119 (10S): : S530 - S531
  • [35] The Impact of Stool Consistency on Bowel Movement Satisfaction in Patients With IBS-C or CIC Treated With Linaclotide or Other Medications Real-World Evidence From the CONTOR Study
    Taylor, Douglas C. A.
    Abel, Jessica L.
    Doshi, Jalpa A.
    Martin, Carolyn
    Hunter, Alyssa Goolsby
    Essoi, Breanna
    Korrer, Stephanie
    Reasner, David S.
    Carson, Robyn T.
    Chey, William D.
    JOURNAL OF CLINICAL GASTROENTEROLOGY, 2019, 53 (10) : 737 - 743
  • [36] Prucalopride (PRU) improves bowel movement (BM) frequency and symptoms (SX) in patients (PTS) with chronic constipation (CC): Results of two double-blind, placebo-controlled trials.
    Johanson, JF
    Miner, PB
    Parkman, HP
    Wojcik, MA
    Lambert, R
    Karcher, K
    Woods, M
    GASTROENTEROLOGY, 2000, 118 (04) : A175 - A175
  • [37] High frequency of secondary, but not primary ocular manifestations of inflammatory bowel disease in patients treated at a tertiary care center
    Walldorf, Jens
    Twarz, Maria
    Schober, Celestina
    Michl, Patrick
    Hammer, Thomas
    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2018, 30 (12) : 1502 - 1506
  • [38] Spontaneous Bowel Movement Frequency Is Improved Over 12 Weeks of Lubiprostone Therapy in Opioid-induced Constipation Patients Regardless of Gender, Age, or Race: Pooled Analysis of Three Well-controlled Studies
    Cryer, Byron
    Mareya, Shadreck
    Joswick, Taryn
    Dolecek, Gayle
    Sun, Yijun
    Ueno, Ryuji
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2013, 108 : S567 - S567
  • [39] Axelopran phase 2B study demonstrates a sustained increase in bowel movement frequency in patients regardeless of duration of opioid-induced constipation
    Vickery, R.
    Webster, L.
    Li, Y.
    Singla, N.
    Canafax, D.
    JOURNAL OF PAIN, 2014, 15 (04): : S77 - S77
  • [40] Efficacy in bowel movement and change of gut microbiota on adult functional constipation patients treated with probiotics-containing products: a systematic review and meta-analysis
    Ding, Fei
    Hu, Mengyang
    Ding, Yifei
    Meng, Yingying
    Zhao, Yanchao
    BMJ OPEN, 2024, 14 (01):