Resveratrol Oligomers from Vatica albiramis

被引：45
|
作者：
Abe, Naohito [1 ]
Ito, Tetsuro [1 ]
Ohguchi, Kenji [2 ]
Nasu, Minori [1 ]
Masuda, Yuichi [1 ]
Oyama, Masayoshi [1 ]
Nozawa, Yoshinori [2 ,3 ]
Ito, Masafumi [2 ]
Iinuma, Munekazu [1 ]
机构：
[1] Gifu Pharmaceut Univ, Lab Pharmacognosy, Gifu 5011196, Japan
[2] Gifu Int Inst Biotechnol, Gifu 5040838, Japan
[3] Tokai Gakuin Univ, Gifu 5048511, Japan
来源：
JOURNAL OF NATURAL PRODUCTS | 2010年 / 73卷 / 09期
关键词：
STEM BARK; THW DIPTEROCARPACEAE; STILBENE GLUCOSIDES; ABSOLUTE STRUCTURES; SHOREA-HEMSLEYANA; AMPELOPSIN-B; CAREX-PUMILA; C-GLUCOSIDES; OLIGOSTILBENES; HOPEAPHENOL;
D O I：
10.1021/np1002675
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Five new stilbenoids, vatalbinosides A-E (1-5), and 13 known compounds (6-18) were isolated from the stem of Vatica albiramis. The effects of these new compounds on interleukin-1 beta-induced production of matrix metalloproteinase-1 (MMP-1) in human dermal fibroblasts were examined. Three resveratrol tetramers, (-)-hopeaphenol (6), vaticanol C (13), and stenophyllol C (14), were identified as strong inhibitors of MMP-1 production.
引用
收藏
页码：1499 / 1506
页数：8
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