The potential of electromembrane extraction for bioanalytical applications

Modern requirements in the field of bioanalysis often involve miniaturized, high-throughput sample preparation techniques that consume low amounts of both sample and potentially hazardous organic solvents. Electromembrane extraction is one technique that meets several of these requirements. In this principle analytes are selectively extracted from a biological matrix, through a supported liquid membrane and into an aqueous acceptor solution. The whole extraction process is facilitated by an electric field across the supported liquid membrane, which greatly reduces the extraction time. This review will give a thorough overview of recent advances in bioanalytical applications involving electromembrane extraction, and discuss both possibilities and challenges of the technique in a bioanalytical setting.